{"id":"W1981972734","doi":"10.1111/j.1600-0854.2010.01144.x","title":"Peroxisome Metabolism and Cellular Aging","year":2010,"lang":"en","type":"review","venue":"Traffic","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Concordia University","keywords":"Peroxisome; Biology; Organelle; Biogenesis; Cell biology; Cellular compartment; Metabolism; Function (biology); Reactive oxygen species; Organelle biogenesis; Flux (metallurgy); Cell metabolism; Mitochondrion; Biochemistry; Cell; Receptor; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001918168,0.0005524846,0.001007772,0.0001424043,0.0001080324,0.00006932417,0.0003471265,0.0009330223,0.00004891824],"category_scores_gemma":[0.00004598624,0.00046591,0.0003411275,0.0001519132,0.0001387819,0.000004579895,0.0001236127,0.000694717,0.00006121685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001444054,"about_ca_system_score_gemma":0.0001873509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001402757,"about_ca_topic_score_gemma":0.000002745685,"domain_scores_codex":[0.9981884,0.0001330821,0.0003835007,0.0007321932,0.0001497405,0.0004130225],"domain_scores_gemma":[0.9990036,0.00001747456,0.0001902023,0.0005514348,0.00004038477,0.0001968584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003914975,0.0000454099,9.179041e-7,0.001861161,0.0001865912,0.000006519994,0.00003267774,0.000001516864,0.02120055,0.00001622229,0.0003496485,0.9762949],"study_design_scores_gemma":[0.000172829,0.00003489817,3.829458e-7,0.0004176,0.0003036369,0.00006491242,0.000008180042,0.000002206948,0.008974289,0.000001174759,0.9895113,0.0005086004],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0184212,0.9803338,0.00001307939,0.00001245844,0.0005380212,0.0004031622,0.00003614086,0.00005328857,0.0001888371],"genre_scores_gemma":[0.001986604,0.9956537,0.000231076,0.00003918662,0.0009447532,0.00007798222,0.0003628849,0.000132613,0.0005711482],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9891617,"threshold_uncertainty_score":0.9997793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704167019648064,"score_gpt":0.2774766182019786,"score_spread":0.260434948005498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}