{"id":"W1981972734","doi":"10.1111/j.1600-0854.2010.01144.x","title":"Peroxisome Metabolism and Cellular Aging","year":2010,"lang":"en","type":"review","venue":"Traffic","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Concordia University","keywords":"Peroxisome; Biology; Organelle; Biogenesis; Cell biology; Cellular compartment; Metabolism; Function (biology); Reactive oxygen species; Organelle biogenesis; Flux (metallurgy); Cell metabolism; Mitochondrion; Biochemistry; Cell; Receptor; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002869955,0.0007560966,0.000982379,0.001550902,0.0003972875,0.0008326517,0.0005574857,0.001100695,0.003294559],"category_scores_gemma":[0.0002362088,0.0001684454,0.0002350565,0.001610231,0.0004941365,0.001060681,0.0007837606,0.000989362,0.003461005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005790766,"about_ca_system_score_gemma":0.0006972439,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000797722,"about_ca_topic_score_gemma":0.0009488378,"domain_scores_codex":[0.9998857,0.00001864905,0.00001420792,0.00002669039,0.00003913719,0.00001569022],"domain_scores_gemma":[0.9998863,0.00002607006,0.00002287362,0.000006642944,0.00003819722,0.00001993036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008224654,0.00005445011,0.0003157535,0.005972939,0.00005028459,0.0004774001,0.0001077463,0.0003457132,0.009933106,0.007699213,0.02172485,0.9532364],"study_design_scores_gemma":[0.000008590901,0.00008146025,0.001661729,0.00112141,0.00004165708,0.003074603,0.00008987836,0.00008310543,0.002005455,0.005464273,0.9863511,0.00001691864],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00030504,0.9973013,0.0002766184,0.0002412296,0.0002054264,0.000003486261,0.00001359425,0.00001368011,0.001639729],"genre_scores_gemma":[0.002249944,0.9950293,0.000300927,0.0001425921,0.0002107556,0.000007312083,0.00004027326,0.000001892264,0.002017022],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003294559,"threshold_uncertainty_score":0.01102138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01704167019648064,"score_gpt":0.2774766182019786,"score_spread":0.260434948005498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}