{"id":"W1981985962","doi":"10.1016/j.bbmt.2012.02.007","title":"HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival","year":2012,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia; Princess Margaret Cancer Centre","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Seattle Genetics; CellGenix; Genentech; Health Resources and Services Administration; Blue Cross and Blue Shield Association; Otsuka America; Teva Pharmaceutical Industries; WellPoint; Celgene; Takeda Oncology; Ariad Pharmaceuticals; Otsuka America Pharmaceutical; Amgen; Swedish Orphan Biovitrum; Sigma-Tau Pharmaceuticals; Kiadis Pharma; Therakos; U.S. Public Health Service; Leukemia and Lymphoma Society; Medical College of Wisconsin; National Institutes of Health; U.S. Department of Health and Human Services; National Marrow Donor Program","keywords":"Medicine; Human leukocyte antigen; Aplastic anemia; Hazard ratio; Immunology; Internal medicine; Sibling; Histocompatibility; Transplantation; Graft-versus-host disease; Bone marrow; Oncology; Gastroenterology; Antigen; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007515487,0.0001721062,0.0002245435,0.000235643,0.000118697,0.0002488735,0.0001255771,0.0001370049,0.0008117604],"category_scores_gemma":[0.0008377227,0.00007266131,0.0002685625,0.0001684255,0.0002294618,0.0002238814,0.0001742166,0.0001969376,0.000102951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001707124,"about_ca_system_score_gemma":0.0001922158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003568245,"about_ca_topic_score_gemma":0.0007213885,"domain_scores_codex":[0.9997255,0.0001303512,0.0000202219,0.0000270649,0.00005902324,0.00003778517],"domain_scores_gemma":[0.9994708,0.0001455088,0.0001641036,0.00003592865,0.00002135379,0.0001623723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004778778,0.0003731158,0.9570445,0.00003001307,0.0003226527,0.000874765,0.00008543162,0.0004208813,0.01484091,0.0001399266,0.0002107214,0.02087829],"study_design_scores_gemma":[0.000128956,0.004886435,0.9859059,0.00001300923,0.0001831704,0.003557154,0.00008631495,0.001371254,0.003280453,0.0001920883,0.0003867531,0.000008506802],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996088,0.0001976586,0.00005384755,0.00001265601,0.000001788814,0.000001648258,0.000009786449,0.000001187239,0.0001125867],"genre_scores_gemma":[0.9998195,0.00005055461,0.00002962882,0.00001078594,0.000003958976,9.221849e-7,0.00003110023,4.196671e-7,0.00005317997],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008117604,"threshold_uncertainty_score":0.003974676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02358568560138048,"score_gpt":0.2978282668034773,"score_spread":0.2742425812020969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}