{"id":"W1982040117","doi":"10.4161/19490976.2014.990784","title":"<i>Lactobacillus rhamnosus</i>CNCM I-3690 and the commensal bacterium<i>Faecalibacterium prausnitzii</i>A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice","year":2014,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":211,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Institut National de la Recherche Agronomique; Crohn's and Colitis Foundation of Canada","keywords":"Lactobacillus rhamnosus; Faecalibacterium prausnitzii; Barrier function; Intestinal permeability; Biology; Microbiology; Probiotic; Gut flora; Tight junction; Occludin; Cell biology; Immunology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001438479,0.0007060351,0.0004724372,0.0003250179,0.000139021,0.0002189505,0.0002632082,0.000390732,0.001256745],"category_scores_gemma":[0.0001210947,0.0001686444,0.0005281065,0.0002672654,0.0001933754,0.0001685103,0.0003039768,0.0006884424,0.0003362289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002012711,"about_ca_system_score_gemma":0.000319301,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001220167,"about_ca_topic_score_gemma":0.001379617,"domain_scores_codex":[0.9996878,0.00005736837,0.0000404352,0.00004789624,0.0001047398,0.00006183143],"domain_scores_gemma":[0.9998178,0.000009378933,0.00007438259,0.00001238852,0.00001973472,0.00006627943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005270372,0.0001154242,0.0002046398,0.00006560848,0.00001159341,0.00003650311,0.000007454987,0.0000461922,0.9978604,0.00002805691,0.00004020224,0.001056908],"study_design_scores_gemma":[0.00007724511,0.004750323,0.007527386,0.00002101303,0.00005224588,0.0004622689,0.00005131961,0.0003293091,0.9834126,0.00003504272,0.003268983,0.00001217361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993614,0.00200544,0.001581493,0.0002262879,0.00006614516,0.00007944431,0.0007872552,0.0001071445,0.001532838],"genre_scores_gemma":[0.9875655,0.001446315,0.005265069,0.0001966656,0.00002084698,0.00008452347,0.001995899,0.00003151677,0.003393681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001256745,"threshold_uncertainty_score":0.004204214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005849010503754797,"score_gpt":0.225142055559271,"score_spread":0.2192930450555162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}