{"id":"W1982040117","doi":"10.4161/19490976.2014.990784","title":"<i>Lactobacillus rhamnosus</i>CNCM I-3690 and the commensal bacterium<i>Faecalibacterium prausnitzii</i>A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice","year":2014,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":211,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Institut National de la Recherche Agronomique; Crohn's and Colitis Foundation of Canada","keywords":"Lactobacillus rhamnosus; Faecalibacterium prausnitzii; Barrier function; Intestinal permeability; Biology; Microbiology; Probiotic; Gut flora; Tight junction; Occludin; Cell biology; Immunology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001000021,0.0004728603,0.0005723597,0.00009405816,0.0002489256,0.0001014442,0.0003961195,0.0003817571,0.00001909143],"category_scores_gemma":[0.0005155449,0.0003653214,0.0001381891,0.0002068651,0.0003172402,0.00001699111,0.0004715553,0.0004446082,0.00003332858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007664142,"about_ca_system_score_gemma":0.0001371883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004168469,"about_ca_topic_score_gemma":0.0007888313,"domain_scores_codex":[0.9969134,0.0008202984,0.0004968494,0.0008954536,0.000132653,0.000741375],"domain_scores_gemma":[0.9985386,0.0001707584,0.0001456794,0.0007318159,0.0001520953,0.0002610948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007142972,0.0001153645,0.003911322,0.0001759402,0.00003900471,0.000002655683,0.0008954736,0.000002318629,0.9918367,0.00002894938,0.0009950425,0.001282957],"study_design_scores_gemma":[0.005276506,0.0009299482,0.08842739,0.0001349702,0.00005397842,0.00008368806,0.0002206669,0.00002222014,0.8465703,0.0001447596,0.05738458,0.0007510468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942151,0.000263696,0.0002266271,0.002623586,0.0002908357,0.001977425,0.00007401707,0.00003314521,0.0002955985],"genre_scores_gemma":[0.9918038,0.00005085434,0.0004960303,0.006931131,0.0002514561,0.0001897116,0.00007471158,0.0000584774,0.0001438907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1452664,"threshold_uncertainty_score":0.9998799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005849010503754797,"score_gpt":0.225142055559271,"score_spread":0.2192930450555162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}