{"id":"W1982079000","doi":"10.1002/em.20410","title":"Tissue‐specific metabolic activation and mutagenicity of 3‐nitrobenzanthrone in Muta™Mouse","year":2008,"lang":"en","type":"article","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Health Canada; National Institutes of Health","keywords":"Nitroreductase; Ames test; Biology; Mutagen; Bone marrow; Carcinogen; Mutant; In vivo; Molecular biology; Biochemistry; Enzyme; Immunology; Genetics; Salmonella; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000780718,0.0001749368,0.0002088973,0.00006951949,0.00007527873,0.000006439026,0.00006618286,0.0001040339,0.00003774199],"category_scores_gemma":[0.000004331849,0.0001831666,0.0000526914,0.00005187057,0.0002166322,0.000007444972,0.0001455996,0.00005540396,0.000002433202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001521195,"about_ca_system_score_gemma":0.0000122419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006573314,"about_ca_topic_score_gemma":0.0000116603,"domain_scores_codex":[0.9990293,0.00005778618,0.0002111652,0.0003709926,0.0001465927,0.0001841112],"domain_scores_gemma":[0.9996248,0.000005848796,0.00006894884,0.0002170942,0.000004864801,0.00007839731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004822734,0.0001400277,0.008330756,0.00001090362,0.0000350179,0.00002041659,0.0001139225,0.00003449955,0.9876305,0.00003023428,0.00001520466,0.003590291],"study_design_scores_gemma":[0.0005952916,0.0001400874,0.1217912,0.000003345408,0.00001504674,0.00004402484,0.0001232854,0.00000918048,0.8738593,0.000009566096,0.00324129,0.0001683565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931731,0.004647033,0.001797593,0.00003365682,0.000018049,0.0002265844,0.00003895381,0.000004445404,0.00006059152],"genre_scores_gemma":[0.9942254,0.004634814,0.0007717378,0.0001051828,0.00002544897,0.00001970143,0.00009070391,0.00002244157,0.0001045064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1137711,"threshold_uncertainty_score":0.7469317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00698516663089283,"score_gpt":0.2074782527311051,"score_spread":0.2004930861002123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}