{"id":"W1982088748","doi":"10.1074/jbc.m607811200","title":"Homooligomeric and Heterooligomeric Associations between K+-Cl– Cotransporter Isoforms and between K+-Cl– and Na+-K+-Cl– Cotransporters","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Cotransporter; Xenopus; Gene isoform; Immunoprecipitation; Yeast; Chemistry; Symporter; Cell biology; Biophysics; Biology; Transporter; Biochemistry; Gene; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005303602,0.0002266718,0.0004060822,0.00005584041,0.0001326389,0.00003343557,0.0001021696,0.0004336548,0.00002599313],"category_scores_gemma":[0.00006425922,0.0001731002,0.0001219015,0.0001158153,0.0002691061,0.00001888741,0.00003672078,0.0002643758,9.830881e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002482958,"about_ca_system_score_gemma":0.00002492278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002971571,"about_ca_topic_score_gemma":0.000001085402,"domain_scores_codex":[0.9985939,0.00002609813,0.0006151097,0.0002899322,0.0001760362,0.0002989137],"domain_scores_gemma":[0.9990169,0.00006703738,0.0003929814,0.0001120813,0.0001172926,0.0002937096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001443686,0.00004568181,0.5618504,0.00003932363,0.0001881153,0.00001202211,0.00007273685,0.000003562848,0.4265892,0.000003268414,0.0001263948,0.01092486],"study_design_scores_gemma":[0.001353309,0.0005270971,0.7959056,0.00003039853,0.0001155565,0.0001354074,0.0001764979,0.000008020242,0.1958701,0.0001324001,0.005399763,0.0003458854],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947078,0.0008292553,0.003790914,0.0002182493,0.00009257496,0.00008542656,0.0000764884,0.00001057146,0.0001886908],"genre_scores_gemma":[0.9975937,0.0008370096,0.0003077139,0.0001678606,0.0007592467,0.000001512738,0.0002091971,0.00001450725,0.0001092542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2340551,"threshold_uncertainty_score":0.7058821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02071019181465672,"score_gpt":0.2555762722922261,"score_spread":0.2348660804775694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}