{"id":"W1982088748","doi":"10.1074/jbc.m607811200","title":"Homooligomeric and Heterooligomeric Associations between K+-Cl– Cotransporter Isoforms and between K+-Cl– and Na+-K+-Cl– Cotransporters","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Cotransporter; Xenopus; Gene isoform; Immunoprecipitation; Yeast; Chemistry; Symporter; Cell biology; Biophysics; Biology; Transporter; Biochemistry; Gene; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700373,0.0001625787,0.0001705687,0.0005405402,0.0003017664,0.000521649,0.0002488906,0.0003704514,0.001552772],"category_scores_gemma":[0.0004830223,0.0002622971,0.0002793646,0.0003460432,0.0003839255,0.0007327743,0.0003279396,0.0003019612,0.0005420189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001994777,"about_ca_system_score_gemma":0.0001879703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004953532,"about_ca_topic_score_gemma":0.0008521906,"domain_scores_codex":[0.9996463,0.00004924879,0.00003661814,0.0001362804,0.00007628259,0.00005525658],"domain_scores_gemma":[0.9993482,0.0001192321,0.0002530733,0.00007197759,0.0001111845,0.00009641812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002027131,0.00003003189,0.01217271,0.000077262,0.00003547504,0.0002466108,0.0001659076,0.00008608546,0.9834167,0.0006131491,0.00009391301,0.00285951],"study_design_scores_gemma":[0.00004587852,0.0002848924,0.4120093,0.00004520762,0.000149778,0.003966531,0.001276842,0.005210422,0.5591524,0.001681288,0.01609762,0.00007985964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929154,0.002064443,0.003394648,0.00009087282,0.00002963612,0.00001084026,0.0001266286,0.00002420066,0.001343455],"genre_scores_gemma":[0.9939626,0.0008515865,0.002618073,0.00009015948,0.00004164174,0.00001498706,0.0004961813,0.00001818866,0.001906559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001552772,"threshold_uncertainty_score":0.005194485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02071019181465672,"score_gpt":0.2555762722922261,"score_spread":0.2348660804775694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}