{"id":"W1982167293","doi":"10.1111/acer.12635","title":"Changes in the Methylation Status of<i><scp>DAT</scp></i>,<i><scp>SERT</scp></i>, and<i>Me<scp>CP</scp>2</i>Gene Promoters in the Blood Cell in Families Exposed to Alcohol During the Periconceptional Period","year":2015,"lang":"en","type":"article","venue":"Alcoholism Clinical and Experimental Research","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation; Western University","funders":"","keywords":"DNA methylation; Methylation; Epigenetics; Promoter; Cord blood; CpG site; Biology; Endocrinology; Pregnancy; Serotonin transporter; Andrology; Molecular biology; Gene; Internal medicine; Medicine; Genetics; Gene expression; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007503543,0.0004500823,0.0007941326,0.0004547691,0.0002845286,0.0001782355,0.0007547477,0.0003213668,0.000005620766],"category_scores_gemma":[0.005266113,0.0002712145,0.0001543779,0.001403935,0.001243734,0.0003230041,0.0006105422,0.00159478,0.00002165304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001478987,"about_ca_system_score_gemma":0.000255891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005989912,"about_ca_topic_score_gemma":0.000465509,"domain_scores_codex":[0.9921356,0.002481458,0.001045496,0.0009783601,0.00195135,0.001407754],"domain_scores_gemma":[0.9916082,0.006711249,0.0001873234,0.0007795127,0.0001858778,0.0005278059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002697899,0.002194569,0.2124112,0.0001849429,0.0000903502,0.0003055703,0.1531039,0.00002849469,0.6287507,0.000169654,0.001012327,0.001478489],"study_design_scores_gemma":[0.0108522,0.002852189,0.3882247,0.0002844401,0.00004673662,0.0001130457,0.1386835,0.0001741805,0.4552058,0.0001814272,0.003270688,0.0001110622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860966,0.008624079,0.000002603635,0.0008497431,0.000197357,0.002848083,0.00003587003,0.00002937033,0.00131628],"genre_scores_gemma":[0.9957883,0.001631646,0.0002350357,0.0008024412,0.0003737474,0.0008119946,0.00005562351,0.00005306375,0.0002481871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1758135,"threshold_uncertainty_score":0.999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1120337843183745,"score_gpt":0.4016198334710865,"score_spread":0.2895860491527119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}