{"id":"W1982194661","doi":"10.1371/journal.ppat.1003124","title":"IFITM Proteins Restrict Viral Membrane Hemifusion","year":2013,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":370,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; U.S. Public Health Service; National Institute on Aging; National Institutes of Health; University of Missouri","keywords":"Lipid bilayer fusion; Cell biology; Biology; Viral envelope; Transmembrane protein; Viral entry; Cell fusion; Hemagglutinin (influenza); Membrane curvature; Membrane protein; Retrovirus; Cell membrane; Biophysics; Membrane; Lipid bilayer; Viral replication; Cell; Biochemistry; Virus; Virology; Glycoprotein; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187867,0.0002434709,0.0001474981,0.0001079911,0.0001340901,0.0001799628,0.0001247879,0.0002344702,0.0005391059],"category_scores_gemma":[0.000131481,0.00008345504,0.0002166857,0.00005796405,0.0001668488,0.0001572358,0.000211084,0.0004329399,0.0002517358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002302954,"about_ca_system_score_gemma":0.0001231544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003694739,"about_ca_topic_score_gemma":0.0002921481,"domain_scores_codex":[0.9998876,0.00001924005,0.00000778821,0.00001778243,0.00003136067,0.00003627709],"domain_scores_gemma":[0.9998835,0.00003585112,0.00003246715,0.00001751295,0.00001421326,0.00001644866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001940002,0.000002431752,0.00006291681,0.000005285109,0.000001044713,0.00001364969,0.000006629188,0.00001595458,0.9994912,0.00004536831,0.000006952937,0.0003291327],"study_design_scores_gemma":[0.000002787349,0.00005704482,0.001358462,0.000001703594,0.000001967724,0.0001419516,0.00001105994,0.0004004665,0.9972619,0.00003482201,0.0007263987,0.000001414614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949114,0.0006256067,0.003321766,0.00004289,0.000006287162,0.00001435088,0.0001153778,0.00004198432,0.0009204465],"genre_scores_gemma":[0.9967037,0.0003337538,0.001850033,0.00004078465,0.000003542059,0.00002095701,0.0002661424,0.00001391508,0.0007671894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005391059,"threshold_uncertainty_score":0.001803458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01346827660182359,"score_gpt":0.2116541583656291,"score_spread":0.1981858817638055,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}