{"id":"W1982197097","doi":"10.1016/j.cell.2006.12.032","title":"A Mechanism for Cell-Cycle Regulation of MAP Kinase Signaling in a Yeast Differentiation Pathway","year":2007,"lang":"en","type":"article","venue":"Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":231,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Cyclin-dependent kinase; Cell biology; MAPK/ERK pathway; Restriction point; Signal transduction; Scaffold protein; Kinase; Phosphorylation; Cell cycle; Cyclin-dependent kinase 2; Biochemistry; Protein kinase A; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001949008,0.00006555673,0.0000689395,0.00005506359,0.00002260858,0.000006282078,0.00007170768,0.00009180432,0.00001339948],"category_scores_gemma":[0.00001406627,0.00006567452,0.0000481566,0.00005373044,0.00001321799,0.000001509481,0.00003586623,0.0000374193,0.000003692069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001003304,"about_ca_system_score_gemma":0.00002664739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007762436,"about_ca_topic_score_gemma":0.00002019305,"domain_scores_codex":[0.9993991,0.00001824638,0.0001548771,0.000161805,0.00009781399,0.0001681966],"domain_scores_gemma":[0.999688,0.00001047828,0.0000526748,0.0001245635,0.00008413822,0.00004019763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000874506,0.0001309336,0.0001915863,0.00008832374,0.00000258255,5.190416e-7,0.0000467538,0.000111761,0.9985883,0.0001510097,0.00002314463,0.0005776448],"study_design_scores_gemma":[0.000627282,0.0001663224,0.001362185,0.00001055399,0.000003313798,2.251769e-7,0.00005286671,0.0008781463,0.9954878,0.001119695,0.0002188907,0.00007273383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789789,0.0001255014,0.01995216,0.00001041547,0.00006413225,0.0002099229,0.00001641202,0.000002678671,0.0006398688],"genre_scores_gemma":[0.9976195,0.000009818212,0.001340528,0.00001456836,0.00008236998,0.00001168384,0.0001121278,0.00001222857,0.0007972474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01864052,"threshold_uncertainty_score":0.2678129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01111572048916796,"score_gpt":0.2426789043775377,"score_spread":0.2315631838883697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}