{"id":"W1982199500","doi":"10.1371/journal.pone.0069248","title":"tRNA Binding to Antitumor Drug Doxorubicin and Its Analogue","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Ferrocene Chemistry and Applications","field":"Chemistry","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Doxorubicin; Drug; Pharmacology; Chemistry; Computational biology; Medicine; Biology; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000309283,0.0001073235,0.0001445953,0.0000237317,0.0001092709,0.00004354973,0.0001418897,0.00004566337,0.00115458],"category_scores_gemma":[0.00005360916,0.0001091209,0.00001965639,0.0001196742,0.00001704735,0.00008454766,0.00006383533,0.0001172077,0.0005806328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002125701,"about_ca_system_score_gemma":0.00001184438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000264747,"about_ca_topic_score_gemma":0.000003437731,"domain_scores_codex":[0.9992985,0.000002722861,0.0001373668,0.0002389067,0.0001264632,0.0001960941],"domain_scores_gemma":[0.9995033,0.0000351562,0.00003808775,0.0002065583,0.00005364561,0.0001632821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002362334,0.0002244092,0.001351614,0.0001774019,0.00003124812,0.00000127527,0.00009819811,7.992043e-7,0.9968674,0.00007223972,0.001090773,0.0000822663],"study_design_scores_gemma":[0.0001471815,0.000003606591,0.0004850712,0.0001251466,0.0000305765,0.000002118379,0.0001179239,0.0002077205,0.9984011,0.00008293599,0.0002543768,0.000142256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857979,0.00008855363,0.000002609463,0.001377223,0.000004300289,0.0001012864,0.0000327137,0.00008107278,0.01251432],"genre_scores_gemma":[0.9905359,0.00002667842,0.0005052831,0.0001172242,0.00012911,0.0001112039,0.00003849297,0.00001540541,0.008520731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004737956,"threshold_uncertainty_score":0.9997585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03470379480574248,"score_gpt":0.2211300037538687,"score_spread":0.1864262089481262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}