{"id":"W1982323848","doi":"10.1139/o08-104","title":"Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells","year":2008,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Natural Compound Pharmacology Studies","field":"Agricultural and Biological Sciences","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Gambogic acid; Matrix metalloproteinase; In vitro; Metastasis; In vivo; Immunocytochemistry; Blot; Breast carcinoma; Chemistry; Gentamicin protection assay; Adhesion; Carcinoma; HeLa; Cancer research; Western blot; Breast cancer; Biochemistry; Cancer; Pathology; Biology; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006673351,0.0002975505,0.0002391965,0.0001923584,0.00008966267,0.0001084425,0.00008603954,0.0001446018,0.0004820226],"category_scores_gemma":[0.00006036048,0.00007187705,0.0001460085,0.00008915223,0.00009853291,0.00007334494,0.00008911882,0.0002675673,0.0001071461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000968716,"about_ca_system_score_gemma":0.000116012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000792213,"about_ca_topic_score_gemma":0.001706236,"domain_scores_codex":[0.9999603,0.00001181434,0.000001722671,0.000003843264,0.00001002769,0.00001232389],"domain_scores_gemma":[0.9999809,0.000004974149,0.000003653743,0.000001947144,0.000003047764,0.000005348936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006023894,0.00001888844,0.00005232497,0.00003341116,0.00000357724,0.00003594189,0.000005900763,0.0000255933,0.9983565,0.00002562361,0.00001623581,0.001365761],"study_design_scores_gemma":[0.00003402112,0.0008790111,0.006613244,0.00001277779,0.00003315545,0.00031372,0.00003508319,0.0004265452,0.9887788,0.00005031808,0.002819124,0.000004103043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992659,0.005102439,0.0007715397,0.0001031261,0.00001923641,0.00001739951,0.0001033254,0.00003120273,0.001192682],"genre_scores_gemma":[0.9939673,0.003329344,0.001351892,0.00006076179,0.00001004518,0.00001580518,0.0001962045,0.000007055191,0.001061517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000792213,"threshold_uncertainty_score":0.001612544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01207257190710294,"score_gpt":0.2275381596171125,"score_spread":0.2154655877100096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}