{"id":"W1982345014","doi":"10.2310/7750.2014.14051","title":"Acitretin-Induced Hepatitis: When to Monitor Cholestatic Enzymes","year":2015,"lang":"en","type":"review","venue":"Journal of Cutaneous Medicine and Surgery","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Acitretin; Medicine; Elevated transaminases; Cholestasis; Hepatitis; Alkaline phosphatase; Toxic hepatitis; Gastroenterology; Transaminase; Ichthyosis; Dermatology; Internal medicine; Enzyme; Psoriasis; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000582542,0.0005348639,0.001341273,0.001497256,0.0001974251,0.0008018444,0.0006339375,0.001106325,0.001941619],"category_scores_gemma":[0.0015941,0.0001795708,0.0004933705,0.001008207,0.0003798137,0.001235543,0.0002660854,0.001424319,0.001215743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003548654,"about_ca_system_score_gemma":0.0005969108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009257412,"about_ca_topic_score_gemma":0.001434995,"domain_scores_codex":[0.9997198,0.00007216673,0.00007012139,0.00003530517,0.00008259702,0.00002003585],"domain_scores_gemma":[0.9993031,0.0003682903,0.000100606,0.00002104147,0.0001683148,0.00003852649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001680561,0.00005708292,0.002029516,0.01316855,0.0001277252,0.002102979,0.0001065713,0.0001915898,0.001885768,0.001409135,0.03498299,0.9437701],"study_design_scores_gemma":[0.00008948493,0.0002242156,0.008616181,0.01840932,0.0005462313,0.04519918,0.0005530224,0.0003156699,0.002771104,0.005068415,0.9181519,0.00005525228],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004299177,0.9966373,0.0002315881,0.001194454,0.0002332338,0.000006245816,0.0000182625,0.00001468434,0.001234192],"genre_scores_gemma":[0.006467255,0.990695,0.0006058714,0.0008136998,0.0005488379,0.00001195172,0.00006571114,0.000005731796,0.0007860342],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001941619,"threshold_uncertainty_score":0.006495357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04821877537172586,"score_gpt":0.327350156885847,"score_spread":0.2791313815141211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}