{"id":"W1982375306","doi":"10.1097/01.jto.0000283409.92625.b0","title":"PD3-2-7: Implications of tumour cavitation on response assessment in trials of Vascular Endothelial Growth Factor Receptor (VEGFR) Inhibitors in combination with platinum-based chemotherapy for advanced non-small cell lung cancer (NSCLC): An analysis of trials conducted by the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG).","year":2007,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; Princess Margaret Cancer Centre; BC Cancer Agency; Ottawa Hospital; Juravinski Cancer Centre; University of Ottawa","funders":"","keywords":"Medicine; Bevacizumab; Chemotherapy; Vascular endothelial growth factor; Lung cancer; Oncology; Angiogenesis; Lung; Cancer research; Internal medicine; Pathology; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03795156,0.0008091477,0.002668242,0.0004963469,0.0003586393,0.001643048,0.001162027,0.002043758,0.003215691],"category_scores_gemma":[0.04041521,0.0005117659,0.004480387,0.001075439,0.001619399,0.001730713,0.0007574629,0.00380607,0.0004486732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001968069,"about_ca_system_score_gemma":0.001994547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001222937,"about_ca_topic_score_gemma":0.003158331,"domain_scores_codex":[0.9708555,0.02498785,0.001380561,0.0009189625,0.0013202,0.000536894],"domain_scores_gemma":[0.9624656,0.02766312,0.006205101,0.001253787,0.001101301,0.00131102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8724622,0.0007822359,0.01130962,0.001221669,0.01093333,0.00006181197,0.0001314417,0.003518542,0.002757875,0.0005948015,0.002025657,0.09420078],"study_design_scores_gemma":[0.6584566,0.1845725,0.0894764,0.0005089559,0.03339107,0.0004990359,0.0001777242,0.01140606,0.004492245,0.00265883,0.01422094,0.0001396354],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9421157,0.03526065,0.004588141,0.005067578,0.0003663787,0.003277416,0.002974492,0.0001762889,0.006173244],"genre_scores_gemma":[0.9920489,0.002246932,0.001917215,0.001044355,0.0001621723,0.0009281859,0.0009749018,0.00004897527,0.000628426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03795156,"threshold_uncertainty_score":0.2007094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06686320572958923,"score_gpt":0.5102595416486647,"score_spread":0.4433963359190755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}