{"id":"W1982407486","doi":"10.4161/nucl.2.4.16266","title":"Composition, recruitment and regulation of the PRC2 complex","year":2011,"lang":"en","type":"article","venue":"Nucleus","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Structural Genomics Consortium","funders":"Canadian Institutes of Health Research","keywords":"PRC2; Regulator; Biology; Histone; Regulation of gene expression; Cell biology; Function (biology); Histone methyltransferase; Epigenetics; Gene; Computational biology; Histone H3; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006178444,0.00004009323,0.0000409117,0.000008055573,0.00004005063,0.000003269292,0.00004944187,0.00003966611,0.00002291394],"category_scores_gemma":[0.000006276522,0.0000306293,0.00002170839,0.0000255174,0.00004973621,0.000001019057,0.00004208668,0.00001611325,9.727571e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002747751,"about_ca_system_score_gemma":0.000007915971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001563364,"about_ca_topic_score_gemma":0.000008538501,"domain_scores_codex":[0.9997001,0.0000255158,0.00008997416,0.00008707876,0.0000491247,0.00004824599],"domain_scores_gemma":[0.9997305,0.000002316891,0.00005577451,0.0001535649,0.0000407636,0.00001703335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001548923,0.00002375948,0.006977315,0.000003977677,0.000008090087,3.297859e-8,0.00008508452,0.000005559314,0.9895256,0.0006007787,0.0001071319,0.002647178],"study_design_scores_gemma":[0.0001298984,0.00007010096,0.4163658,0.000003890951,0.000005472719,7.094999e-7,0.000008973251,0.00004974258,0.5723525,0.0006117595,0.01036703,0.00003410387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995512,0.0001798689,0.000415698,0.00004552499,0.00004832081,0.0001517424,0.000005635482,0.00000290111,0.003638309],"genre_scores_gemma":[0.9978339,0.00006218242,0.001920939,0.0000429668,0.00002670414,0.000004778303,0.00001801236,0.000005601015,0.00008492373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4171731,"threshold_uncertainty_score":0.1249027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08049991475055525,"score_gpt":0.2742811820205391,"score_spread":0.1937812672699839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}