{"id":"W1982412876","doi":"10.2741/1823","title":"Involvement of SMAD4, but not of SMAD2, in transforming growth factor-beta1-induced trophoblast expression of matrix metalloproteinase-2","year":2006,"lang":"en","type":"article","venue":"Frontiers in bioscience","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Centers for Disease Control and Prevention; Chinese Academy of Sciences; Queen's University; National Natural Science Foundation of China","keywords":"Transforming growth factor; Trophoblast; Matrix metalloproteinase; Retrovirus; Cell culture; Cell biology; Complementary DNA; Biology; Molecular biology; Recombinant DNA; Secretion; Viral vector; Metalloproteinase; Extracellular matrix; Chemistry; Gene; Placenta; Genetics; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003306451,0.0005019253,0.0002159013,0.0003720222,0.0002312102,0.0003861311,0.000198283,0.0003058349,0.001510857],"category_scores_gemma":[0.000259311,0.0002424683,0.000327909,0.0001439988,0.0003160531,0.0002662443,0.0002178377,0.0003701487,0.0003599943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001701447,"about_ca_system_score_gemma":0.0002999362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003014852,"about_ca_topic_score_gemma":0.000392753,"domain_scores_codex":[0.9998643,0.00004599868,0.00001141301,0.00001720635,0.00002924707,0.00003178854],"domain_scores_gemma":[0.9998434,0.00004932731,0.00004204856,0.00001701719,0.00001961031,0.00002854263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005965636,0.00003777652,0.0009382498,0.0001164069,0.00001316588,0.0004086654,0.00003612976,0.00009023964,0.9954783,0.0002509704,0.00003186616,0.002001667],"study_design_scores_gemma":[0.0001048898,0.000524324,0.01796388,0.00002035279,0.0000833049,0.00185163,0.0001513637,0.001512685,0.9739583,0.0002991334,0.003517851,0.00001239606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900398,0.003718949,0.002908683,0.0001778465,0.00004936053,0.00002898876,0.000174878,0.00002897431,0.002872503],"genre_scores_gemma":[0.9905171,0.002370308,0.003129322,0.00006427198,0.00002651126,0.00004076755,0.0002914639,0.00001078438,0.003549399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001510857,"threshold_uncertainty_score":0.005054355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.020570722145443,"score_gpt":0.2527209420782437,"score_spread":0.2321502199328007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}