{"id":"W1982415075","doi":"10.1159/000305354","title":"Evolution of Clinical and Molecular Responses to Bexarotene Treatment in Cutaneous T-Cell Lymphoma","year":2010,"lang":"en","type":"article","venue":"Dermatology","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"Bexarotene; Cutaneous T-cell lymphoma; clone (Java method); Medicine; Lymphoma; Peripheral blood; Peripheral T-cell lymphoma; T cell; Mycosis fungoides; Internal medicine; Immunology; Gastroenterology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003788166,0.0001496785,0.000310681,0.0004763865,0.0002550531,0.0003307954,0.0001267984,0.0002936118,0.0009108441],"category_scores_gemma":[0.001430749,0.0001033273,0.000173274,0.0003570258,0.0002323173,0.0001969301,0.0001205775,0.0002459011,0.0001714769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002600929,"about_ca_system_score_gemma":0.0001039319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004404417,"about_ca_topic_score_gemma":0.0004263727,"domain_scores_codex":[0.9996628,0.0001210463,0.00003398152,0.00006680554,0.00005878865,0.00005670713],"domain_scores_gemma":[0.9987069,0.0003598496,0.0005971601,0.0000541634,0.0001059702,0.0001759234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002099599,0.00008710091,0.9773837,0.00002977411,0.00005407011,0.001699095,0.000101119,0.0001194686,0.00970577,0.00002023924,0.00005653464,0.008643487],"study_design_scores_gemma":[0.00005514517,0.001366542,0.9863945,0.00000615398,0.00005861044,0.008976385,0.00009549781,0.0001864617,0.002509638,0.00001958347,0.0003262151,0.000005246207],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993281,0.0002985773,0.00008477886,0.000008863637,0.000001186508,0.000006782157,0.00004012595,0.000003327359,0.0002283012],"genre_scores_gemma":[0.9997638,0.00005975289,0.00005139505,0.000008525858,0.000004009617,0.000003916413,0.00006207691,8.821704e-7,0.00004568412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009108441,"threshold_uncertainty_score":0.003047109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008135414224371114,"score_gpt":0.2828229006658937,"score_spread":0.2746874864415225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}