{"id":"W1982418790","doi":"10.1038/mp.2008.31","title":"Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?","year":2008,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute on Aging; National Institutes of Health","keywords":"Arachidonic acid; Carbamazepine; Pharmacology; Valproic Acid; Lithium (medication); Epilepsy; Bipolar disorder; Medicine; Mood stabilizer; Phospholipase A2; Chemistry; Internal medicine; Enzyme; Biochemistry; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005162039,0.000894331,0.002456103,0.001083513,0.0002958609,0.001372355,0.001407605,0.001629004,0.004351562],"category_scores_gemma":[0.0004274216,0.0002572217,0.0005655842,0.001238453,0.000560764,0.001579858,0.000492911,0.001784035,0.002901826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005463337,"about_ca_system_score_gemma":0.0009019859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009437209,"about_ca_topic_score_gemma":0.001731457,"domain_scores_codex":[0.999854,0.00002012626,0.000020458,0.0000284663,0.00005878285,0.00001811284],"domain_scores_gemma":[0.9998201,0.00007256231,0.00003368927,0.000006472517,0.00004781722,0.00001935583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002577966,0.0001221843,0.0002306327,0.0106637,0.000166615,0.0004966491,0.0000599807,0.0003650217,0.006119315,0.003954174,0.02060023,0.9569637],"study_design_scores_gemma":[0.0001667705,0.0003826171,0.00233572,0.004424456,0.000461735,0.004432937,0.0002071571,0.0003383806,0.002581054,0.006178258,0.9784365,0.0000543822],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002616069,0.9969312,0.000375489,0.00064666,0.0003339946,0.000007298751,0.00002486907,0.00001274651,0.001406082],"genre_scores_gemma":[0.001154586,0.9971673,0.0003411848,0.0002874755,0.0003230806,0.000007963947,0.00002611646,9.843427e-7,0.0006912246],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004351562,"threshold_uncertainty_score":0.01455742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02520020511667428,"score_gpt":0.3400730684198173,"score_spread":0.3148728633031431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}