{"id":"W1982479568","doi":"10.1007/s00018-008-8305-x","title":"Proliferating cell nuclear antigen: a proteomics view","year":2008,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":232,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sudbury Regional Hospital","funders":"Canadian Institutes of Health Research","keywords":"Proliferating cell nuclear antigen; DNA replication; Biology; Cell biology; Chromatin; Proteomics; DNA polymerase; Replication factor C; DNA polymerase delta; DNA clamp; DNA; Molecular biology; Computational biology; Eukaryotic DNA replication; Genetics; Polymerase chain reaction; Gene; Reverse transcriptase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000428067,0.0005820183,0.0009315393,0.0001389453,0.0004640968,0.0001241149,0.0006833211,0.0004817195,0.00001309712],"category_scores_gemma":[0.0001255162,0.0004917046,0.0004839929,0.000319477,0.0004581575,0.000009614125,0.0004722785,0.0002661653,0.00004862499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001698632,"about_ca_system_score_gemma":0.0007173138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005778001,"about_ca_topic_score_gemma":6.750311e-7,"domain_scores_codex":[0.9970495,0.0002750244,0.0005492361,0.001187726,0.0003837986,0.000554783],"domain_scores_gemma":[0.9987202,0.00001212659,0.0003448968,0.0005628195,0.00006162506,0.0002982965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002700424,0.0004726775,0.00001850947,0.02029156,0.0005490823,0.0005726828,0.0003150277,0.00001948825,0.6094701,0.001987533,0.005230415,0.3610459],"study_design_scores_gemma":[0.0001462217,0.0003189954,7.415173e-8,0.0008650221,0.0001030354,0.0001866419,0.00003871255,0.00004477343,0.02414672,0.00003338272,0.9734616,0.0006548094],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003009041,0.9920772,0.001011837,0.00001394098,0.0001953212,0.001190384,0.00001510035,0.00004054246,0.002446673],"genre_scores_gemma":[0.0004891317,0.9911897,0.007413734,0.00026552,0.0001972406,0.00008327508,0.0000815594,0.00009263542,0.0001871714],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9682312,"threshold_uncertainty_score":0.9997535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02184962072661267,"score_gpt":0.26781965750814,"score_spread":0.2459700367815273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}