{"id":"W1982499259","doi":"10.1016/j.jaci.2010.05.015","title":"IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7–mediated Fas ligand cleavage from bronchial epithelial cells","year":2010,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Fas ligand; Matrix metalloproteinase; Respiratory epithelium; Cytokine; Proinflammatory cytokine; Immunology; Immune system; Gene knockdown; Epithelium; Biology; Cell biology; Apoptosis; Inflammation; Cancer research; Medicine; Pathology; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006017812,0.0006003982,0.000624745,0.0005983972,0.0004836763,0.0009336914,0.0002853892,0.0008379523,0.005716332],"category_scores_gemma":[0.0005048458,0.0004441906,0.0009057502,0.0002880874,0.0003437244,0.0006514954,0.000840056,0.002109106,0.002055822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008174482,"about_ca_system_score_gemma":0.0007298764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001252922,"about_ca_topic_score_gemma":0.002041673,"domain_scores_codex":[0.9987595,0.0002473354,0.0001050447,0.00009054485,0.000322457,0.0004751568],"domain_scores_gemma":[0.999613,0.0001042529,0.00003660212,0.00005523967,0.0001026218,0.0000883306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00113361,0.00007680005,0.0009202792,0.0001269492,0.00002864837,0.0004123723,0.00008705001,0.00007029726,0.9939605,0.0001908286,0.0003643243,0.00262839],"study_design_scores_gemma":[0.0002384359,0.0006613355,0.02872092,0.00005017526,0.00006974554,0.001240528,0.000565082,0.001959796,0.9602754,0.0003620503,0.005835993,0.00002049498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850318,0.004502895,0.003230609,0.0007709995,0.000315288,0.0001482322,0.001199318,0.00009197208,0.004708854],"genre_scores_gemma":[0.9874445,0.001539178,0.002642474,0.0003363305,0.0001256066,0.000125036,0.002011582,0.00002723886,0.005748076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005716332,"threshold_uncertainty_score":0.01912302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01132018134113634,"score_gpt":0.2867201298560493,"score_spread":0.275399948514913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}