{"id":"W1982519429","doi":"10.1054/mehy.2000.1187","title":"An exploratory approach to the serotonergic hypothesis of depression: bridging the synaptic gap","year":2001,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Treatment of Major Depression","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University","funders":"","keywords":"Serotonergic; Bridging (networking); Neuroscience; Psychology; Depression (economics); Psychiatry; Serotonin; Medicine; Computer science; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009537278,0.0002502807,0.0004230278,0.0001024294,0.000221061,0.00002633113,0.0006447073,0.0001571424,0.0004322913],"category_scores_gemma":[0.001504079,0.0001122768,0.000145457,0.0003847686,0.0003081859,0.0001060514,0.0001490041,0.0003337275,0.00009710413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004529493,"about_ca_system_score_gemma":0.0001322704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003608006,"about_ca_topic_score_gemma":0.00001105641,"domain_scores_codex":[0.9969895,0.0003650007,0.0003940469,0.0004302476,0.001421765,0.0003994777],"domain_scores_gemma":[0.99734,0.0008272356,0.0001143907,0.001173387,0.00007411344,0.0004708493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002047199,0.006741716,0.1215839,0.0003937201,0.0009371764,0.0007716617,0.006936574,0.0005884527,0.01045675,0.0005322491,0.02259324,0.8264173],"study_design_scores_gemma":[0.01500297,0.004507178,0.6328498,0.006459516,0.003023094,0.006436395,0.01808508,0.03243164,0.08499541,0.002068121,0.1916775,0.002463353],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809147,0.001787752,0.002015813,0.0068642,0.0001494809,0.001016863,0.000004382248,0.0001566921,0.007090125],"genre_scores_gemma":[0.9951002,0.0001998575,0.001242379,0.002315397,0.0005066235,0.0001913398,0.000004470541,0.00005178863,0.000387969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.823954,"threshold_uncertainty_score":0.4733286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06470738498230551,"score_gpt":0.2933578616265545,"score_spread":0.228650476644249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}