{"id":"W1982548570","doi":"10.1002/ajh.23299","title":"Platelet count or bleeding as the outcome in ITP trials?","year":2012,"lang":"en","type":"letter","venue":"American Journal of Hematology","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Canadian Blood Services","funders":"","keywords":"Romiplostim; Medicine; Eltrombopag; Rituximab; Randomized controlled trial; Clinical trial; Surrogate endpoint; Intensive care medicine; Population; Immune thrombocytopenia; Clinical endpoint; Platelet transfusion; Thrombopoietin; Internal medicine; Platelet; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.4544697,0.001707256,0.008445543,0.005267889,0.002494786,0.01359918,0.006600582,0.01475874,0.00550826],"category_scores_gemma":[0.7090202,0.001289578,0.004807137,0.007234109,0.01313285,0.01189691,0.005355264,0.02030175,0.001610364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006689488,"about_ca_system_score_gemma":0.007294327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001581687,"about_ca_topic_score_gemma":0.002392715,"domain_scores_codex":[0.3308742,0.5620548,0.06285997,0.01044121,0.03225261,0.00151725],"domain_scores_gemma":[0.1416959,0.7915735,0.03593449,0.01124544,0.01678481,0.002765953],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01320294,0.0003246038,0.02539495,0.07185846,0.02159868,0.0005088009,0.004377116,0.001285391,0.0003303939,0.1012149,0.3421142,0.4177895],"study_design_scores_gemma":[0.01473181,0.004647426,0.01724545,0.1861009,0.01680554,0.001403529,0.002682948,0.004967225,0.001045838,0.2384282,0.5112233,0.0007177886],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.003234851,0.3958626,0.01367041,0.5156949,0.06155127,0.001354878,0.0008889853,0.0001604663,0.007581664],"genre_scores_gemma":[0.1229072,0.08759467,0.02766296,0.629273,0.1227024,0.006420775,0.0007611484,0.0006110583,0.002066677],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.5455303,"threshold_uncertainty_score":0.672736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05369372569810282,"score_gpt":0.354241109787535,"score_spread":0.3005473840894322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}