{"id":"W1982802055","doi":"10.1007/s10969-011-9121-3","title":"Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771","year":2012,"lang":"en","type":"article","venue":"Journal of Structural and Functional Genomics","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Structural Genomics Consortium","funders":"National Institute of General Medical Sciences; Office of Science; National Institutes of Health","keywords":"Structural genomics; Helix-turn-helix; Dimer; Protein structure; DNA; Biology; DNA-binding domain; Protein family; Sequence motif; Crystallography; Helix (gastropod); Structural motif; Bacteroides thetaiotaomicron; Nuclear magnetic resonance spectroscopy; Chemistry; DNA-binding protein; Stereochemistry; Biochemistry; Genetics; Transcription factor; Gene; Bacteroides","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000122274,0.0002333651,0.0003264959,0.0001882164,0.0003249231,0.0003011689,0.0001986587,0.0004191515,0.001120789],"category_scores_gemma":[0.0001941683,0.000136143,0.0001706964,0.0002037694,0.0002862885,0.0003895101,0.0001233649,0.0005788532,0.0003419058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004573111,"about_ca_system_score_gemma":0.0001665406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005703187,"about_ca_topic_score_gemma":0.0005304509,"domain_scores_codex":[0.9999359,0.000007213715,0.000004645689,0.00001612729,0.00001655727,0.00001959248],"domain_scores_gemma":[0.9998622,0.0000273742,0.00002974804,0.0000145424,0.00002100218,0.00004509362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002786878,0.00007805403,0.001516615,0.00006124054,0.00002037404,0.0002905701,0.000135128,0.0004310569,0.9914316,0.0008570968,0.001171197,0.003728401],"study_design_scores_gemma":[0.00007372304,0.0003448449,0.01841724,0.00001059377,0.00004227618,0.001527037,0.0003732716,0.009680208,0.9601297,0.0008848583,0.008474668,0.00004164378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951226,0.0004244036,0.002313658,0.0002294592,0.00002612428,0.00001284518,0.0003220349,0.00008455019,0.001464314],"genre_scores_gemma":[0.9958384,0.0001712699,0.002010064,0.00007917965,0.000009141109,0.00001264987,0.001147179,0.00002157096,0.0007104623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001120789,"threshold_uncertainty_score":0.003749371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01509855014006804,"score_gpt":0.2160119748883432,"score_spread":0.2009134247482752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}