{"id":"W1982861385","doi":"10.1007/s00394-012-0459-5","title":"An atherogenic diet decreases liver FXR gene expression and causes severe hepatic steatosis and hepatic cholesterol accumulation: effect of endurance training","year":2012,"lang":"en","type":"article","venue":"European Journal of Nutrition","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Steatosis; Internal medicine; Cholesterol; Endocrinology; Medicine; Gene expression; Fatty liver; Endurance training; Gene; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000803529,0.000160243,0.0004078164,0.0001284108,0.00006852876,0.00002481674,0.00005482008,0.00003317703,0.00001523388],"category_scores_gemma":[0.0001071293,0.0001206413,0.00008513638,0.00007495918,0.00005081889,0.000441365,0.00002281916,0.0001538699,0.000001508183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001511193,"about_ca_system_score_gemma":0.00001049526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002539856,"about_ca_topic_score_gemma":7.908693e-7,"domain_scores_codex":[0.998363,0.0006751652,0.0004291238,0.000124894,0.0002333775,0.0001744848],"domain_scores_gemma":[0.999004,0.0001370882,0.0003456521,0.0001446233,0.00008864969,0.0002799543],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002101344,0.000841524,0.3267772,0.001028397,0.000121668,0.00006856046,0.005566246,0.000006459213,0.6344509,0.000002703992,0.00004689911,0.02898818],"study_design_scores_gemma":[0.008042908,0.002103425,0.9352434,0.002240869,0.0005233517,0.001392752,0.0002699943,0.0001231687,0.04945719,0.000003857278,0.0004555197,0.0001436145],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918095,0.007550356,0.0002254074,0.00003628783,0.0001141111,0.0002259127,0.000009534294,0.00001065581,0.00001827643],"genre_scores_gemma":[0.9960693,0.001751691,0.001173582,0.00008433321,0.0008741659,0.000002765067,0.000008925847,0.00003011644,0.000005157356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6084662,"threshold_uncertainty_score":0.4919608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03694314486071029,"score_gpt":0.2858448555858982,"score_spread":0.2489017107251879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}