{"id":"W1982864136","doi":"10.1074/jbc.275.20.14949","title":"Modulation of Rho and Cytoskeletal Protein Attachment to Membranes by a Prenylcysteine Analog","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université du Québec à Montréal","funders":"","keywords":"Prenylation; Cysteine; Geranylgeranylation; Chemistry; RHOA; Actin; Biochemistry; Actin-binding protein; Cytoskeleton; Actin cytoskeleton; Enzyme; Cell; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001413758,0.0002987142,0.0001934222,0.0001537938,0.0001467722,0.0002019098,0.0002501283,0.0003556656,0.0009050131],"category_scores_gemma":[0.0001263771,0.0001408146,0.000276086,0.0001172465,0.0002493335,0.0002043313,0.0002357401,0.0005537795,0.000266728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003227013,"about_ca_system_score_gemma":0.000259307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004446638,"about_ca_topic_score_gemma":0.0007378901,"domain_scores_codex":[0.9998257,0.00004410825,0.00001301051,0.00002884345,0.00004288654,0.00004547407],"domain_scores_gemma":[0.9999099,0.00001370462,0.00002757906,0.00001327728,0.000009206738,0.00002643147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001526608,0.00002506362,0.00002071994,0.00001192623,0.000002938006,0.00001961705,0.00000537936,0.00001737383,0.9993824,0.00005447519,0.000007385216,0.0003000305],"study_design_scores_gemma":[0.00002501826,0.0002724305,0.0006884913,0.000002271614,0.000007924107,0.00009018036,0.00001208171,0.0002949192,0.9972894,0.00003394115,0.001280511,0.00000276875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970955,0.0009453453,0.0007947885,0.00008812176,0.00001531605,0.00001919379,0.00008430372,0.00002860032,0.0009288319],"genre_scores_gemma":[0.9957561,0.0006292237,0.001114516,0.00004452463,0.00000949698,0.00003654493,0.0003387227,0.00001572318,0.002055159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009050131,"threshold_uncertainty_score":0.003027558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01936920764769907,"score_gpt":0.2992057865685516,"score_spread":0.2798365789208526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}