{"id":"W1982916236","doi":"10.1038/srep01465","title":"High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring","year":2013,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Offspring; Bursting; Metabolite; Folic acid; Gestation; Folic acid supplementation; Neural tube; Biological neural network; Biology; Pharmacology; Internal medicine; Endocrinology; Pregnancy; Neuroscience; Medicine; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006846612,0.00009584567,0.000230547,0.0001647691,0.00005635949,0.00002315251,0.00003450582,0.00005710742,0.000304594],"category_scores_gemma":[0.00006244539,0.0000765816,0.0000450076,0.0002427584,0.0002386085,0.0001625936,0.00003481146,0.00009403281,0.00000629879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002996211,"about_ca_system_score_gemma":0.0000546656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002281044,"about_ca_topic_score_gemma":0.00004848311,"domain_scores_codex":[0.9985799,0.00004112685,0.0004748637,0.0004719694,0.0002363231,0.0001958167],"domain_scores_gemma":[0.9993215,0.00002253634,0.0001367282,0.0003328622,0.00007683159,0.0001095742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000367406,0.00008652914,0.03503432,0.0001824046,0.000009519706,0.0002795652,0.0007973078,0.00000454596,0.940797,0.00002117935,0.0002866324,0.02246426],"study_design_scores_gemma":[0.001300811,0.0002745594,0.3860737,0.000217232,0.00005094252,0.000940993,0.000581152,0.0003339711,0.601069,0.00826065,0.0007040304,0.0001929438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978129,0.0001701206,0.0001217496,0.0005193646,0.000613436,0.000618602,0.000001637145,0.00001763825,0.0001245658],"genre_scores_gemma":[0.9980217,0.000007518042,0.001418163,0.00004101618,0.00001427873,0.00001964721,0.00006190835,0.000006924702,0.0004088397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3510394,"threshold_uncertainty_score":0.3335091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01233126474470133,"score_gpt":0.2607775717422819,"score_spread":0.2484463069975806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}