{"id":"W1982960788","doi":"10.1002/hep.20723","title":"Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir†","year":2005,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":258,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-Luc","funders":"","keywords":"Adefovir; Lamivudine; Virology; Strain (injury); Biology; Medicine; Hepatitis B virus; Virus; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000195614,0.0001397624,0.0005035007,0.0001397268,0.00009432536,0.000005369335,0.00005380905,0.00005916959,0.00007414972],"category_scores_gemma":[0.0002184728,0.0001226854,0.00002676925,0.0001983757,0.0002154377,0.00004739681,0.00005906641,0.0001038712,0.00001936197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006480774,"about_ca_system_score_gemma":0.00007188597,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000597657,"about_ca_topic_score_gemma":0.1287388,"domain_scores_codex":[0.998869,0.00006730766,0.0003172853,0.0003305729,0.00013812,0.0002777129],"domain_scores_gemma":[0.9993098,0.00008669434,0.00006699382,0.0002726538,0.0001302395,0.0001335741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000153907,0.00009821494,0.950229,0.0001104993,0.00005898309,0.00003970805,0.001921431,0.000002690965,0.04254093,0.003094549,0.000850407,0.0008996527],"study_design_scores_gemma":[0.001389258,0.001078504,0.9761356,0.0002092549,0.00009068381,0.000039411,0.0002908957,0.00005061094,0.01202757,0.0001901992,0.008275785,0.0002222372],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905521,0.0001389511,0.0003761739,0.00481268,0.000018337,0.0005289954,0.00006573041,0.00004766907,0.003459404],"genre_scores_gemma":[0.9928879,0.00001560755,0.005470208,0.0008787697,0.00004377611,0.00004323102,0.000009838646,0.00001736452,0.0006332792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1281412,"threshold_uncertainty_score":0.8871594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03420731172257936,"score_gpt":0.3272823689889242,"score_spread":0.2930750572663449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}