{"id":"W1983031676","doi":"10.1016/s0040-4039(02)00741-4","title":"Synthesis of the racemic tetracyclic core of CP-225,917: use of a strain-assisted Cope rearrangement","year":2002,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Oxidative Organic Chemistry Reactions","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Strain (injury); Cope rearrangement; Core (optical fiber); Stereochemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003235342,0.0003779485,0.0003890215,0.000334906,0.0002825966,0.0003308503,0.0007094996,0.0003368614,0.003325578],"category_scores_gemma":[0.0003262084,0.0001787346,0.0002754724,0.0002983968,0.000229305,0.0005113988,0.0003713446,0.0006007098,0.001800391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003697413,"about_ca_system_score_gemma":0.0007657059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004785079,"about_ca_topic_score_gemma":0.0009331377,"domain_scores_codex":[0.9998422,0.00001815663,0.0000136279,0.00003461285,0.00003907298,0.00005240019],"domain_scores_gemma":[0.9998237,0.00001761474,0.00003462918,0.0000393911,0.0000319411,0.00005263572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004762827,0.0001685598,0.0002543677,0.0001597786,0.00004621098,0.0004089331,0.0001181465,0.001361601,0.9630453,0.005802214,0.000838587,0.02731997],"study_design_scores_gemma":[0.00005101517,0.0008721842,0.0004532317,0.000006808188,0.00002516071,0.0002352957,0.00001670772,0.00106638,0.9886873,0.0004271641,0.008133548,0.00002526456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9223718,0.001024237,0.04486962,0.0002764597,0.0001792337,0.0003484573,0.001499618,0.0005819547,0.02884859],"genre_scores_gemma":[0.9668705,0.0008446582,0.02248287,0.0001431472,0.0000273956,0.0001346849,0.001175123,0.0001604677,0.008161058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003325578,"threshold_uncertainty_score":0.01112521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05302877930038132,"score_gpt":0.2387540622503255,"score_spread":0.1857252829499442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}