{"id":"W1983043684","doi":"10.1016/j.bpj.2012.11.764","title":"Correlation of Sodium Channels Transcripts of Single DRG Neuron to their Electrophysiological and Pharmacological Profiles","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Sodium channel; Electrophysiology; Neuron; Patch clamp; Neuroscience; Tetrodotoxin; NAV1; Nociception; Current clamp; Gene isoform; Voltage clamp; Biology; Chemistry; Biophysics; Sodium; Receptor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004917537,0.0001380528,0.0002348464,0.00007783213,0.00008395066,0.00003903247,0.000210328,0.00004496959,0.0000276646],"category_scores_gemma":[0.0001237491,0.00009069705,0.00008748497,0.0002825561,0.0001740022,0.0002551209,0.00004848828,0.0002467393,0.000008385926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001047027,"about_ca_system_score_gemma":0.00001146674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001574513,"about_ca_topic_score_gemma":1.486347e-8,"domain_scores_codex":[0.9988925,0.00009256435,0.0002687567,0.0002450496,0.0002242676,0.0002768882],"domain_scores_gemma":[0.9994714,0.0001385343,0.0001072284,0.0000680959,0.00004457668,0.000170219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006627751,0.000185581,0.00001196452,0.000008218106,0.000001498222,0.000006039732,0.00006043776,0.0001615418,0.9977398,0.0002160056,0.00003710045,0.001505528],"study_design_scores_gemma":[0.0002026273,0.001818879,0.003532983,0.00001364118,0.000006585272,0.00005023474,0.00001028397,0.006846476,0.9871795,0.0002115759,0.0000326171,0.00009461835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983941,0.000005778717,0.00059651,0.0003918079,0.000322596,0.0002221528,0.00000374751,0.00002290513,0.0000404514],"genre_scores_gemma":[0.99941,0.00003189643,0.00005331457,0.0003213359,0.0001461621,0.000008287423,1.836995e-7,0.000008767933,0.00002009699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01056033,"threshold_uncertainty_score":0.3698518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0398425443223669,"score_gpt":0.2554726922758957,"score_spread":0.2156301479535288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}