{"id":"W1983056569","doi":"10.1186/1471-2121-15-2","title":"Differential effects of PDCD4 depletion on protein synthesis in myoblast and myotubes","year":2014,"lang":"en","type":"article","venue":"BMC Cell Biology","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; York University","keywords":"Myogenesis; P70-S6 Kinase 1; mTORC1; Biology; Cell biology; Amino acid; Myocyte; Protein biosynthesis; Biochemistry; Phosphorylation; Protein kinase B","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008006616,0.0001021765,0.0001670334,0.00006269405,0.00001857067,0.000003504215,0.00006519809,0.0001703518,0.000009305119],"category_scores_gemma":[0.0001476952,0.00008817017,0.00003907466,0.00003440645,0.00006784197,0.000001184806,0.00004124208,0.00004444934,0.000003011701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002666446,"about_ca_system_score_gemma":0.000007866101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002253571,"about_ca_topic_score_gemma":0.00003865507,"domain_scores_codex":[0.9992306,0.000216742,0.0001385866,0.0002437872,0.00003306022,0.0001372633],"domain_scores_gemma":[0.9996818,0.00006359001,0.0000542644,0.0001551622,0.00001512003,0.00003004979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000172368,0.0001039983,0.00750315,0.0001720401,0.000003855632,1.479064e-7,0.000006412883,0.000001406467,0.9870913,0.0002425354,0.00001871833,0.004684078],"study_design_scores_gemma":[0.0007579569,0.0004643265,0.04767035,0.00003540949,0.000009192644,4.907479e-7,0.000003919582,0.00005419098,0.9491369,0.0001483063,0.001624505,0.00009448219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978772,0.0002180603,0.001263222,0.00001356118,0.00008370021,0.0002207054,0.000006235026,0.000004638214,0.0003127224],"genre_scores_gemma":[0.9993062,0.0001205425,0.0002794671,0.00002661951,0.0001305281,0.00005998828,0.00003989996,0.000008855636,0.00002786844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0401672,"threshold_uncertainty_score":0.3595475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004197596883901379,"score_gpt":0.1976183374316537,"score_spread":0.1934207405477523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}