{"id":"W1983057094","doi":"10.1016/j.mce.2014.07.023","title":"GPER-independent effects of estrogen in rat aortic vascular endothelial cells","year":2014,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials","funders":"Heart and Stroke Foundation of Canada","keywords":"GPER; Downregulation and upregulation; Estrogen receptor; MAPK/ERK pathway; Endocrinology; Apoptosis; Internal medicine; Biology; Estrogen; Phosphorylation; Cell biology; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000244397,0.0003013452,0.0003395372,0.0003093465,0.0001756174,0.000308933,0.0002930818,0.0002290114,0.001713943],"category_scores_gemma":[0.0002013137,0.0001664341,0.0004534052,0.0003336008,0.0003244547,0.0004334761,0.0003085466,0.0006349549,0.0004409037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003065486,"about_ca_system_score_gemma":0.0002806168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001891561,"about_ca_topic_score_gemma":0.0023973,"domain_scores_codex":[0.9998197,0.00003657939,0.00001292678,0.00002806191,0.00003926927,0.00006356125],"domain_scores_gemma":[0.999873,0.00003500537,0.00001517452,0.00003192051,0.0000173156,0.00002763592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009351356,0.0001170435,0.0001990447,0.00009021403,0.00001467343,0.0004263647,0.00006386008,0.00008298344,0.994765,0.0003055439,0.0001329628,0.002867093],"study_design_scores_gemma":[0.0001544025,0.0009465808,0.02355721,0.00002159263,0.00005950742,0.0005261716,0.0001375103,0.0004073597,0.9687636,0.0002704073,0.005144024,0.00001160662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884804,0.005172087,0.001107127,0.0002818336,0.00008514652,0.00002032335,0.0008616565,0.00007045659,0.003920887],"genre_scores_gemma":[0.9842188,0.004137614,0.001109552,0.0001896691,0.00005249311,0.00003394239,0.001549373,0.00002038365,0.008688225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001891561,"threshold_uncertainty_score":0.005733669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002120750183979599,"score_gpt":0.1903056066074338,"score_spread":0.1881848564234542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}