{"id":"W1983065003","doi":"10.1371/journal.pone.0043990","title":"Liuwei Dihuang (LWDH), a Traditional Chinese Medicinal Formula, Protects against β-Amyloid Toxicity in Transgenic Caenorhabditis elegans","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island; National Research Council Canada; Nova Scotia Department of Agriculture","funders":"Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; China Academy of Chinese Medical Sciences; Department of Agriculture, Nova Scotia","keywords":"Caenorhabditis elegans; Oxidative stress; Reactive oxygen species; Gallic acid; Juglone; DPPH; Biochemistry; Chemistry; Transgene; Pharmacology; Biology; Cell biology; Antioxidant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007046818,0.0004417174,0.0002324728,0.0003510565,0.0001254548,0.0001172912,0.000154786,0.0001911029,0.0006697422],"category_scores_gemma":[0.00006329634,0.00009583081,0.0002432115,0.0002023564,0.0001161143,0.0001648235,0.0001351272,0.0003810125,0.0001011419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001529898,"about_ca_system_score_gemma":0.0001647442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006107137,"about_ca_topic_score_gemma":0.00135073,"domain_scores_codex":[0.9999716,0.000003018345,0.000002847575,0.000006840286,0.00000841153,0.000007156277],"domain_scores_gemma":[0.9999586,0.000004254716,0.00001556393,0.000002987053,0.000006370817,0.000012209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002338728,0.00006803959,0.0003502032,0.000143905,0.00001398321,0.00005727497,0.00001075802,0.00005021779,0.9944631,0.00003092073,0.00005008664,0.004527627],"study_design_scores_gemma":[0.0001209344,0.002088276,0.02343249,0.00002519755,0.0001152269,0.0002632914,0.00004447108,0.0005801173,0.9680946,0.00006949442,0.005151126,0.00001475487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923199,0.003791533,0.002093206,0.0001359589,0.00004016368,0.0000456986,0.0006265615,0.00008780698,0.0008590182],"genre_scores_gemma":[0.9867103,0.004492334,0.004677462,0.0001440515,0.00002345511,0.00005352359,0.0009391494,0.00001783486,0.002942017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006697422,"threshold_uncertainty_score":0.002240539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03157706410913501,"score_gpt":0.2197839900280718,"score_spread":0.1882069259189367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}