{"id":"W1983097979","doi":"10.1016/j.ydbio.2011.07.031","title":"Cks85A and Skp2 interact to maintain diploidy and promote growth in Drosophila","year":2011,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor","funders":"Cancer Research Society","keywords":"Biology; Ubiquitin ligase; Null allele; SKP2; RNA interference; Cell biology; Ubiquitin; Gene knockdown; Gene; Cell cycle; Cyclin-dependent kinase; Cyclin; Endoreduplication; Mutant; Null cell; Function (biology); Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000174934,0.0001489373,0.0001401153,0.0000764878,0.00004118298,0.00000916008,0.0001032817,0.0001345183,0.00003223143],"category_scores_gemma":[0.0000582283,0.0001361681,0.00001589639,0.00006572334,0.00009219369,0.000003941605,0.0003024136,0.00008004849,0.00001749954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001611078,"about_ca_system_score_gemma":0.00003328174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004640337,"about_ca_topic_score_gemma":0.00009392761,"domain_scores_codex":[0.9991181,0.00005600692,0.0001734269,0.0003720815,0.00002783915,0.0002525747],"domain_scores_gemma":[0.9997613,0.000007431613,0.00003105712,0.00007503219,0.00001796659,0.0001071895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001739736,0.00005845237,0.1255881,0.00001892197,0.00002726741,0.00001592549,0.001142577,1.195742e-8,0.8631976,0.001427522,0.00006366859,0.008286044],"study_design_scores_gemma":[0.0007107691,0.0006819019,0.1346103,0.0000290143,0.000003707661,0.0001572051,0.0002831715,0.000002013053,0.8528218,0.003375507,0.006958839,0.000365683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964277,0.0001756126,0.0000780844,0.0001324,0.00006179018,0.000265892,0.00001824385,0.000009656603,0.002830675],"genre_scores_gemma":[0.991678,0.00009715107,0.007300504,0.0006735824,0.00003561854,0.00005167328,0.0000677173,0.00001319652,0.00008258441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0103757,"threshold_uncertainty_score":0.5552772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01736708627405496,"score_gpt":0.2391765481379851,"score_spread":0.2218094618639302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}