{"id":"W1983099248","doi":"10.1002/cbic.200500110","title":"Methyl Groups as Probes of Structure and Dynamics in NMR Studies of High‐Molecular‐Weight Proteins","year":2005,"lang":"en","type":"review","venue":"ChemBioChem","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":199,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biomolecule; Protonation; Chemistry; Monomer; Molecule; Residue (chemistry); Molecular dynamics; Small molecule; Computational chemistry; Biochemistry; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002116556,0.001139996,0.001255781,0.002404434,0.000441177,0.0008756454,0.001510049,0.001852413,0.001643675],"category_scores_gemma":[0.0008018444,0.0007693354,0.0003589628,0.002468233,0.001353752,0.001714882,0.0009981485,0.001962709,0.003255182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001119813,"about_ca_system_score_gemma":0.0006051868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001207806,"about_ca_topic_score_gemma":0.00248455,"domain_scores_codex":[0.9996141,0.00009200597,0.00002535011,0.00007957465,0.0001554135,0.00003364599],"domain_scores_gemma":[0.9995828,0.0001982315,0.00005723186,0.00002966503,0.00009675748,0.00003534834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001606341,0.0001439446,0.0002915611,0.0112689,0.00008569192,0.0005108266,0.000181277,0.0009656684,0.04219025,0.02336329,0.01380306,0.9070349],"study_design_scores_gemma":[0.0000329472,0.0001399437,0.000745033,0.0009882143,0.00005960826,0.002118901,0.00007446536,0.0002944567,0.01405874,0.004081082,0.977357,0.00004957757],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003039987,0.9968016,0.0008936012,0.0001377617,0.0001669618,0.000009999562,0.000008064507,0.000008029251,0.001669988],"genre_scores_gemma":[0.002794152,0.9933044,0.001960941,0.0002018005,0.0001884144,0.00002411585,0.00002377514,0.000003864962,0.001498388],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002404434,"threshold_uncertainty_score":0.01119357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01904652755988154,"score_gpt":0.3018313849300657,"score_spread":0.2827848573701842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}