{"id":"W1983134388","doi":"10.1158/1538-7445.am2014-ct105","title":"Abstract CT105: MK-3475 (anti-PD-1 monoclonal antibody) for non-small cell lung cancer (NSCLC): Antitumor activity and association with tumor PD-L1 expression","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Lung cancer; Internal medicine; Oncology; Monoclonal antibody; Immunohistochemistry; Cohort; Cancer; Antibody; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001512047,0.0002789525,0.000495524,0.0002332091,0.0004086037,0.0001240596,0.000199027,0.0001772634,0.0002719637],"category_scores_gemma":[0.00009271169,0.0002179436,0.0001233616,0.000384215,0.0001745039,0.0002275885,0.0000637761,0.0006472612,0.000005626783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008273321,"about_ca_system_score_gemma":0.0009189103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003369828,"about_ca_topic_score_gemma":0.0005161909,"domain_scores_codex":[0.997215,0.0001148934,0.0002840564,0.0006761992,0.0008592024,0.0008506846],"domain_scores_gemma":[0.9981958,0.0004128199,0.0002329697,0.0003774118,0.0005285017,0.0002524664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005661466,0.0001727945,0.132278,0.001000548,0.0001402905,0.00001447888,0.0002216287,0.00001195718,0.8458335,0.000003985138,0.008963238,0.005698122],"study_design_scores_gemma":[0.005602102,0.0004482301,0.4700415,0.001196111,0.00007400462,0.0000047302,0.00008459217,0.000683071,0.5115155,0.000008293524,0.01005639,0.0002854736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993221,0.001938136,0.0003819564,0.001469919,0.0002880492,0.001627574,0.0001882728,0.00004734045,0.0008377597],"genre_scores_gemma":[0.9944643,0.001774616,0.0003329067,0.0002296682,0.0007065447,0.0006068879,0.00004136734,0.00007316898,0.001770477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3377635,"threshold_uncertainty_score":0.8887483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03218367493266629,"score_gpt":0.3776240989429154,"score_spread":0.3454404240102491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}