{"id":"W1983146096","doi":"10.1126/science.1214448","title":"iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against <i>Listeria</i> and Responses to LPS","year":2012,"lang":"en","type":"article","venue":"Science","topic":"Listeria monocytogenes in Food Safety","field":"Biochemistry, Genetics and Molecular Biology","cited_by":334,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Listeria; Tumor necrosis factor alpha; Listeria monocytogenes; Chemistry; Microbiology; Immunology; Medicine; Biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137318,0.0002480933,0.0002255327,0.0001984187,0.0001994298,0.0004569473,0.0002918761,0.0003325925,0.001882462],"category_scores_gemma":[0.0001366254,0.0001805064,0.0001527574,0.0000948133,0.0003574041,0.0001989074,0.0003657683,0.0005896725,0.0007368287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002492306,"about_ca_system_score_gemma":0.0001253415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001872776,"about_ca_topic_score_gemma":0.0003835314,"domain_scores_codex":[0.9998243,0.00002982387,0.00001368193,0.00004816682,0.00003283336,0.00005119939],"domain_scores_gemma":[0.9997764,0.00002236754,0.0000823252,0.00003315192,0.0000147076,0.00007102441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002372272,0.00002194107,0.0002307419,0.00001589896,0.000001970663,0.00004786939,0.000009194649,0.00002830517,0.9987845,0.00008227827,0.00005437977,0.0004856798],"study_design_scores_gemma":[0.00004427298,0.0001671145,0.01491269,0.000009224568,0.00001109993,0.0002775437,0.00006190912,0.001607741,0.9795191,0.0000660397,0.003314969,0.000008417427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954954,0.0006372503,0.001565713,0.0001196127,0.00002802407,0.00001086976,0.0002661475,0.0001383604,0.00173868],"genre_scores_gemma":[0.9962509,0.0001601048,0.0006673726,0.00005742167,0.000009839433,0.00002069172,0.0003584268,0.00005054524,0.002424726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001882462,"threshold_uncertainty_score":0.006297469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0502710780813239,"score_gpt":0.3125680424164557,"score_spread":0.2622969643351318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}