{"id":"W1983146096","doi":"10.1126/science.1214448","title":"iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against <i>Listeria</i> and Responses to LPS","year":2012,"lang":"en","type":"article","venue":"Science","topic":"Listeria monocytogenes in Food Safety","field":"Biochemistry, Genetics and Molecular Biology","cited_by":334,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Listeria; Tumor necrosis factor alpha; Listeria monocytogenes; Chemistry; Microbiology; Immunology; Medicine; Biology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007424828,0.00008178279,0.00008992574,0.00005872329,0.00009719826,0.00002303846,0.0001564127,0.00006011237,0.000003223201],"category_scores_gemma":[0.0004954484,0.00007495661,0.00001827711,0.0002242129,0.0002712492,0.00002193701,0.0001918237,0.00002500628,0.000004689918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002931611,"about_ca_system_score_gemma":0.00007295109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009511859,"about_ca_topic_score_gemma":0.00000669163,"domain_scores_codex":[0.9991576,0.00006181922,0.0001596399,0.0002402792,0.0001630293,0.0002176047],"domain_scores_gemma":[0.9993895,0.00001197349,0.00008725844,0.0002865471,0.0001119843,0.0001126783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002465783,0.00001554991,0.002098009,0.000007826488,0.000002960317,7.040602e-8,0.00007709742,0.000009370553,0.9953251,0.00003028868,0.00004135652,0.002145724],"study_design_scores_gemma":[0.0002521624,0.0001859843,0.06985769,0.00001174101,0.000003761879,0.000006582667,0.00004566539,0.0000438036,0.9158349,0.00001122857,0.01364924,0.00009724849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969581,0.0002503341,0.001262995,0.0001797388,0.0002858064,0.0003309546,0.00001967098,0.00000960372,0.0007028345],"genre_scores_gemma":[0.9983928,0.00001947565,0.0009697785,0.0003124129,0.0001052616,0.00002718125,0.00000926857,0.0000070688,0.0001567864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07949028,"threshold_uncertainty_score":0.3056642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0502710780813239,"score_gpt":0.3125680424164557,"score_spread":0.2622969643351318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}