{"id":"W1983147534","doi":"10.1111/j.1471-4159.2011.07473.x","title":"Loss of activated CaMKII at the synapse underlies Alzheimer’s disease memory loss","year":2011,"lang":"en","type":"letter","venue":"Journal of Neurochemistry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Synapse; Neuroscience; Alzheimer's disease; Disease; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001869502,0.0005884697,0.0008716696,0.0009061003,0.0003035175,0.0005457326,0.0004333253,0.0006714477,0.001677758],"category_scores_gemma":[0.0004327676,0.0002523857,0.0004360571,0.000414856,0.0003472216,0.0004882163,0.0004477749,0.001084481,0.0005919207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003585857,"about_ca_system_score_gemma":0.0001247834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009327977,"about_ca_topic_score_gemma":0.0006553262,"domain_scores_codex":[0.9998528,0.00001162957,0.00002001384,0.00004293788,0.00004095305,0.00003161928],"domain_scores_gemma":[0.9997918,0.00001074524,0.0001099065,0.00001675053,0.00003794828,0.00003295517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004583128,0.0007891278,0.208455,0.001010607,0.0008508068,0.01334156,0.0006000723,0.0003038183,0.6908244,0.001703754,0.004593577,0.07294419],"study_design_scores_gemma":[0.000132804,0.0005709642,0.9383667,0.0001296568,0.0004093308,0.02092734,0.0002387193,0.001727265,0.0295012,0.003638829,0.004315058,0.00004207326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710924,0.02127446,0.001428432,0.0005765382,0.00020199,0.00005062851,0.0005244896,0.0001309249,0.0047201],"genre_scores_gemma":[0.9955396,0.002823972,0.0002625705,0.0001668004,0.0001222803,0.00001939477,0.0002608325,0.000007747292,0.0007967529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001677758,"threshold_uncertainty_score":0.005612612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08244628429281099,"score_gpt":0.330633169164556,"score_spread":0.2481868848717451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}