{"id":"W1983228670","doi":"10.1371/journal.pgen.1003208","title":"Telomerase-Null Survivor Screening Identifies Novel Telomere Recombination Regulators","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China; School of Medicine, New York University; York University; Brandeis University","keywords":"Telomere; Telomerase; Biology; Homologous recombination; Genetics; Gene; Chromatin; Helicase; Telomere-binding protein; DNA repair; RAD52; Cell biology; RAD51; RNA; DNA-binding protein; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000218449,0.0003903923,0.0005364321,0.0003678153,0.0002328484,0.0001452633,0.0002829141,0.0002428097,0.000836035],"category_scores_gemma":[0.0002740409,0.0003723474,0.0001643698,0.0006198231,0.0001804233,0.0002534686,0.0001224522,0.0003420927,0.0005182654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008597642,"about_ca_system_score_gemma":0.0001033459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001438483,"about_ca_topic_score_gemma":0.000050955,"domain_scores_codex":[0.9972216,0.00006244551,0.0006638964,0.0006247077,0.0007884154,0.0006389735],"domain_scores_gemma":[0.9979025,0.0001426519,0.0002172197,0.0007877102,0.0005585491,0.0003913635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000992832,0.001244113,0.1319048,0.0005520286,0.0004217394,0.00003598849,0.001222143,0.00006152812,0.807373,0.0003459826,0.008564725,0.04817463],"study_design_scores_gemma":[0.003658083,0.0005604042,0.3136123,0.0006266945,0.0004418111,0.0001506316,0.001483363,0.01398586,0.6541772,0.0008145164,0.009190866,0.00129836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939028,0.001017496,0.0005198523,0.001259151,0.0005062934,0.0009450366,0.00002420313,0.0002832003,0.001541953],"genre_scores_gemma":[0.9868888,0.0002741788,0.007827125,0.000577857,0.0003558575,0.00008174949,0.000114547,0.0001053351,0.003774569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1817074,"threshold_uncertainty_score":0.9998729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03422104255070504,"score_gpt":0.2517704006410262,"score_spread":0.2175493580903212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}