{"id":"W1983254277","doi":"10.1007/s10897-008-9161-4","title":"Genetic Testing of Children at Risk for Adult Onset Conditions: When is Testing Indicated?","year":2008,"lang":"en","type":"article","venue":"Journal of Genetic Counseling","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Genetic counseling; Genetic testing; Family history; Colorectal cancer; Medicine; MLH1; Disease; Cancer; Age of onset; Lynch syndrome; Young adult; Genetics; Gerontology; Internal medicine; DNA mismatch repair; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001281126,0.0002131522,0.0003788298,0.000613274,0.0008608428,0.0007739065,0.0003978297,0.002923642,0.001717882],"category_scores_gemma":[0.007608508,0.0001623708,0.0001801547,0.0005018834,0.001139665,0.001209014,0.0003729746,0.001777953,0.000289033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005670586,"about_ca_system_score_gemma":0.001107794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003670618,"about_ca_topic_score_gemma":0.004981677,"domain_scores_codex":[0.999196,0.0003069474,0.00009897337,0.00006527675,0.0001517223,0.0001810774],"domain_scores_gemma":[0.9972116,0.001654319,0.0004213838,0.00006152154,0.0002843068,0.0003668156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004564087,0.0001755007,0.4982584,0.0003502535,0.00003320464,0.3398799,0.0045212,0.0006689147,0.006026114,0.00362641,0.01944699,0.1265568],"study_design_scores_gemma":[0.00008777577,0.0009326634,0.1875744,0.002754962,0.0001409674,0.7201995,0.02276389,0.001950772,0.006624899,0.0081223,0.0487428,0.0001051586],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8219303,0.03038236,0.004616341,0.1201031,0.0008858419,0.0001193686,0.0002066494,0.0001771278,0.02157897],"genre_scores_gemma":[0.9699247,0.01323603,0.005932961,0.008693709,0.0009601219,0.00003097166,0.00008006736,0.0000360029,0.001105441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003670618,"threshold_uncertainty_score":0.007298529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02918279645678988,"score_gpt":0.273176351079866,"score_spread":0.2439935546230761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}