{"id":"W1983270011","doi":"10.1038/ng.2247","title":"A genome-wide association meta-analysis identifies new childhood obesity loci","year":2012,"lang":"en","type":"review","venue":"Nature Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":438,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Ontario Institute for Cancer Research; McMaster University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Mental Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; ZonMw; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs; National Institute for Health and Care Research; British Heart Foundation; Wellcome Trust","keywords":"Biology; Genome-wide association study; Childhood obesity; Meta-analysis; Genetics; Genetic association; Obesity; Computational biology; Association (psychology); Evolutionary biology; Single-nucleotide polymorphism; Gene; Genotype; Overweight","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003235442,0.001613457,0.002907184,0.002025772,0.0002062653,0.001255801,0.001439357,0.001341292,0.001503277],"category_scores_gemma":[0.003530632,0.0005112294,0.001960439,0.003204618,0.0004365143,0.0006547783,0.0009280894,0.001866423,0.000433302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000628294,"about_ca_system_score_gemma":0.001540709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002541895,"about_ca_topic_score_gemma":0.006264159,"domain_scores_codex":[0.9991602,0.0002119058,0.00009616106,0.0002791922,0.0002046463,0.00004795576],"domain_scores_gemma":[0.9974693,0.001752246,0.0002806594,0.0001218696,0.0002844562,0.00009159456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0009489215,0.00007471943,0.02562711,0.01378556,0.01355034,0.000863953,0.00005615617,0.0007830268,0.002493782,0.00212555,0.02246922,0.9172217],"study_design_scores_gemma":[0.0009696229,0.0007711739,0.2309947,0.02021817,0.0837421,0.01367107,0.0003917978,0.002299336,0.006193381,0.02956491,0.6107244,0.0004593174],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.001443378,0.9945772,0.001622248,0.00138798,0.0002743019,0.000006375873,0.0002476518,0.00002640557,0.0004144709],"genre_scores_gemma":[0.01270884,0.9813637,0.003101835,0.001165145,0.0007529712,0.00002250947,0.0004818409,0.00001306675,0.0003902926],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003235442,"threshold_uncertainty_score":0.01711088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03503552564385885,"score_gpt":0.315116088536158,"score_spread":0.2800805628922991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}