{"id":"W1983277991","doi":"10.1046/j.1365-2249.2003.02187.x","title":"HIV-1 infection is facilitated in T cells by decreasing p56lck protein tyrosine kinase activity","year":2003,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canadian Blood Services; University of Manitoba; Toronto General Hospital","funders":"Vlaamse regering","keywords":"Jurkat cells; Biology; Tyrosine kinase; Cell culture; Viral replication; Kinase; T cell; Cell biology; Virus; Virology; Signal transduction; Molecular biology; Immunology; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004969029,0.0003186326,0.0005715797,0.000134322,0.0001983994,0.00002107472,0.0001700998,0.0005941758,0.002419769],"category_scores_gemma":[0.0002923983,0.0002929996,0.0001995995,0.0002300371,0.0008046079,0.0001609978,0.0001215078,0.0007900433,0.004509107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002556989,"about_ca_system_score_gemma":0.0001169423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008232016,"about_ca_topic_score_gemma":0.00002371297,"domain_scores_codex":[0.9962347,0.001623175,0.000639718,0.0006854793,0.00005510059,0.0007617881],"domain_scores_gemma":[0.9990011,0.0002897354,0.0001419604,0.0004406181,0.0000473744,0.00007917057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008755568,0.003867819,0.01453329,0.000005833955,0.0002232385,0.0000317612,0.0002112432,2.693841e-7,0.9737723,0.0001041674,0.002735563,0.003638958],"study_design_scores_gemma":[0.005754597,0.001561889,0.009564457,0.00002910947,0.00001205805,0.00002679462,0.0001641656,0.000001495858,0.943341,0.00004781254,0.03924485,0.0002518392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905181,0.006660015,0.00005891422,0.0002055954,0.0005252908,0.0008113053,0.0001216941,0.00008289424,0.001016207],"genre_scores_gemma":[0.9961612,0.0002257052,0.0001191499,0.0001256369,0.00001022858,0.0002205785,0.0002139598,0.00002505047,0.002898456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03650929,"threshold_uncertainty_score":0.9999522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03559476111666462,"score_gpt":0.353030420606265,"score_spread":0.3174356594896004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}