{"id":"W1983317208","doi":"10.1021/bi0261387","title":"Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for <i>Shigella flexneri</i> Y Lipopolysaccharide:  X-ray Structures and Thermodynamics<sup>,</sup>","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Trisaccharide; Chemistry; Oligosaccharide; Stereochemistry; Shigella flexneri; Epitope; Hydrogen bond; Crystallography; Side chain; Molecule; Antigen; Biochemistry; Escherichia coli; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001426365,0.0002637012,0.0002284175,0.00004782555,0.00009643636,0.00005137971,0.0002517962,0.0003136734,0.000203314],"category_scores_gemma":[0.0001051463,0.0002650481,0.000137981,0.0000841655,0.0001808169,0.000007962816,0.0001033967,0.0001381183,0.000006572477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002049452,"about_ca_system_score_gemma":0.00003441194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001979053,"about_ca_topic_score_gemma":0.000001114685,"domain_scores_codex":[0.9984737,0.00003930243,0.0003346455,0.0005642229,0.0002422143,0.0003459007],"domain_scores_gemma":[0.999106,0.00002662162,0.000133018,0.0004021706,0.0001766429,0.0001555421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000108597,0.00006978639,0.00007124562,0.0001006913,0.00006164538,0.000002478247,0.00003313013,0.00006721525,0.9812255,0.00003820383,0.003023627,0.01519789],"study_design_scores_gemma":[0.0008092151,0.0001411572,0.00002713109,0.00002323482,0.00001667071,0.00001827758,0.00008667645,0.002597757,0.9884453,0.0002974605,0.007237567,0.0002995722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915029,0.005037018,0.001705227,0.0002141329,0.00003499058,0.0003873572,0.0005742285,0.00001453405,0.0005295991],"genre_scores_gemma":[0.9951034,0.001086835,0.002163556,0.0001125224,0.0001957177,0.00007576606,0.0006173886,0.00004213221,0.000602698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01489831,"threshold_uncertainty_score":0.9999802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594587773066843,"score_gpt":0.2420409655233799,"score_spread":0.2260950877927115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}