{"id":"W1983317208","doi":"10.1021/bi0261387","title":"Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for <i>Shigella flexneri</i> Y Lipopolysaccharide:  X-ray Structures and Thermodynamics<sup>,</sup>","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences","keywords":"Trisaccharide; Chemistry; Oligosaccharide; Stereochemistry; Shigella flexneri; Epitope; Hydrogen bond; Crystallography; Side chain; Molecule; Antigen; Biochemistry; Escherichia coli; Organic chemistry; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008701099,0.000193064,0.00007910643,0.00007464423,0.00008699705,0.0001728563,0.0002761634,0.0001492086,0.0008052744],"category_scores_gemma":[0.00009398803,0.00009597988,0.0001480303,0.0000588855,0.000182397,0.00009666361,0.00007951688,0.0002209432,0.0002401443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004124732,"about_ca_system_score_gemma":0.0001126921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00180284,"about_ca_topic_score_gemma":0.001075343,"domain_scores_codex":[0.9999509,0.000004678438,0.000001614535,0.000007337382,0.00001830497,0.00001712748],"domain_scores_gemma":[0.9999684,0.000006798603,0.000007278035,0.000002099041,0.000007660747,0.000007807522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008863899,0.00001601973,0.00118156,0.00001815041,0.000007974542,0.00002693539,0.00001677493,0.0007560839,0.9967073,0.0002039968,0.00006951352,0.0009069675],"study_design_scores_gemma":[0.0000263005,0.0001801219,0.01040756,0.000003852334,0.00001290111,0.0001447143,0.00003340153,0.007927283,0.9796907,0.0001404231,0.001426615,0.00000631271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979814,0.0002104993,0.001090573,0.00002801237,0.000003968459,0.000002777224,0.00005041256,0.00001560129,0.000616844],"genre_scores_gemma":[0.998448,0.00009352806,0.0006110328,0.00002281501,0.000002700345,0.000003625494,0.0002054152,0.00000682094,0.0006059271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00180284,"threshold_uncertainty_score":0.003584743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594587773066843,"score_gpt":0.2420409655233799,"score_spread":0.2260950877927115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}