{"id":"W1983397539","doi":"10.1002/jps.21624","title":"Biowaiver monographs for immediate release solid oral dosage forms: Rifampicin","year":2009,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Bioequivalence; Dosage form; Bioavailability; Pharmacology; Active ingredient; Excipient; Rifampicin; Drug; Pharmacokinetics; Biopharmaceutics Classification System; Medicine; Chemistry; Tuberculosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004413572,0.000274123,0.0005385422,0.0003185241,0.0005668661,0.000102593,0.0007714736,0.0002686172,0.0003609419],"category_scores_gemma":[0.000295178,0.0001991378,0.0004373042,0.0006337712,0.0007513684,0.0007554736,0.00004847594,0.000853339,0.0000551853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007380193,"about_ca_system_score_gemma":0.0002193106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000515513,"about_ca_topic_score_gemma":0.000003631093,"domain_scores_codex":[0.9969032,0.0004108642,0.0009804077,0.0003171774,0.0005449872,0.0008433862],"domain_scores_gemma":[0.9975675,0.0007335166,0.0005276734,0.000117205,0.0002843309,0.0007697466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01261624,0.006293907,0.0289483,0.0004461071,0.001308239,0.0008653216,0.004824282,0.007558379,0.1841441,0.03484329,0.1762035,0.5419483],"study_design_scores_gemma":[0.008980868,0.004023694,0.002724394,0.0001174575,0.0007153248,0.0004431832,0.001101439,0.03659318,0.07043182,0.01518268,0.8588672,0.0008187192],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724063,0.005018425,0.002187937,0.01071144,0.004586164,0.0007930942,0.0001412321,0.00007592997,0.004079433],"genre_scores_gemma":[0.9914359,0.0008704439,0.001024302,0.00552121,0.0009205954,0.00000702861,0.000003927064,0.000009726926,0.0002068851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6826637,"threshold_uncertainty_score":0.8120604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1876423669813541,"score_gpt":0.4994877934083631,"score_spread":0.311845426427009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}