{"id":"W1983440297","doi":"10.1177/0091270010395940","title":"Anti‐EGFR Monoclonal Antibodies for Treatment of Colorectal Cancers: Development of Cetuximab and Panitumumab","year":2011,"lang":"en","type":"review","venue":"The Journal of Clinical Pharmacology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Panitumumab; Cetuximab; Medicine; Bevacizumab; Colorectal cancer; Epidermal growth factor receptor; Monoclonal antibody; Clinical trial; Oncology; Internal medicine; Adjuvant; EGFR inhibitors; Pharmacology; Cancer; Antibody; Immunology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007496997,0.0007696174,0.00163453,0.003373852,0.0002247243,0.0007112923,0.0008093728,0.000916901,0.00300987],"category_scores_gemma":[0.0004703554,0.0003158347,0.0006316045,0.00261713,0.0004045559,0.001132509,0.0006067574,0.001712321,0.002315817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000480153,"about_ca_system_score_gemma":0.0008756333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008395676,"about_ca_topic_score_gemma":0.001901408,"domain_scores_codex":[0.9997508,0.00005117126,0.00003540922,0.00003713056,0.0001058583,0.000019697],"domain_scores_gemma":[0.9998134,0.0000754436,0.00003512169,0.000006789107,0.00004714826,0.00002208185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001332265,0.0001540493,0.000125419,0.01869818,0.0001413176,0.0003524517,0.00006625168,0.000310071,0.00314456,0.002493013,0.01335496,0.9610264],"study_design_scores_gemma":[0.00009887953,0.0003222819,0.001472277,0.004137913,0.0002313574,0.003659689,0.00006223564,0.0001432016,0.001724969,0.001612633,0.9865049,0.00002981193],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001750344,0.9987295,0.0001477004,0.0001258706,0.00007079661,0.000008441574,0.00001147666,0.000005525075,0.0007255769],"genre_scores_gemma":[0.000739089,0.9984081,0.0002251093,0.0001104252,0.00006369642,0.000007583063,0.00001759114,0.000001056565,0.0004272407],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003373852,"threshold_uncertainty_score":0.01006895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2655273053984388,"score_gpt":0.5152066995027675,"score_spread":0.2496793941043287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}