{"id":"W1983440297","doi":"10.1177/0091270010395940","title":"Anti‐EGFR Monoclonal Antibodies for Treatment of Colorectal Cancers: Development of Cetuximab and Panitumumab","year":2011,"lang":"en","type":"review","venue":"The Journal of Clinical Pharmacology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Panitumumab; Cetuximab; Medicine; Bevacizumab; Colorectal cancer; Epidermal growth factor receptor; Monoclonal antibody; Clinical trial; Oncology; Internal medicine; Adjuvant; EGFR inhibitors; Pharmacology; Cancer; Antibody; Immunology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009537066,0.0003732083,0.0050139,0.0001503477,0.00009266914,0.000002576355,0.0001833759,0.0002155063,0.00008032387],"category_scores_gemma":[0.000115678,0.0001856267,0.0008881287,0.0001067307,0.0005934453,0.0000331162,0.0000821047,0.0002411188,0.00000108139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002726624,"about_ca_system_score_gemma":0.002152059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000270956,"about_ca_topic_score_gemma":0.00002515267,"domain_scores_codex":[0.996384,0.000306263,0.002662598,0.0002016769,0.0001871374,0.0002582714],"domain_scores_gemma":[0.9945728,0.002042879,0.00269817,0.0001180825,0.0004265862,0.000141532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006121636,0.001521255,0.0007255712,0.00439114,0.01000932,0.00003086509,0.001037149,4.610513e-7,0.00002859215,0.00001003057,0.0009304802,0.9751935],"study_design_scores_gemma":[0.01132822,0.01698131,0.003230496,0.002360679,0.02359715,0.0004044849,0.0001783304,0.000005984583,0.0005145079,0.00003947837,0.9411269,0.0002324113],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08563915,0.9116793,0.00001182053,0.00008293792,0.001169494,0.00114484,0.00007273456,0.000004059679,0.00019568],"genre_scores_gemma":[0.01340281,0.9843917,0.001451004,0.000040868,0.0005389174,0.00004937388,0.000007972637,0.00002849069,0.00008886989],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9749611,"threshold_uncertainty_score":0.7569636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2655273053984388,"score_gpt":0.5152066995027675,"score_spread":0.2496793941043287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}