{"id":"W1983536185","doi":"10.1097/aln.0b013e3181e2c1a1","title":"Metabolic Profiling of Hearts Exposed to Sevoflurane and Propofol Reveals Distinct Regulation of Fatty Acid and Glucose Oxidation","year":2010,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Heart and Stroke Foundation of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Propofol; Sevoflurane; Glucose transporter; Beta oxidation; CD36; Fatty acid; Fatty acid metabolism; Medicine; Carbohydrate metabolism; Oxidative phosphorylation; Metabolism; Endocrinology; Internal medicine; Biochemistry; Pharmacology; Chemistry; Insulin; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002854145,0.00008984554,0.0003857579,0.00008265187,0.00003092904,0.000002161451,0.00002159895,0.000137802,0.0000150426],"category_scores_gemma":[0.0002278638,0.00006608001,0.00003898654,0.0000890721,0.0001174984,0.0000350382,0.00002712005,0.00009080807,0.000001280725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003008399,"about_ca_system_score_gemma":0.00002751776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001767064,"about_ca_topic_score_gemma":0.000003778358,"domain_scores_codex":[0.9993023,0.00005299968,0.0002528014,0.0001942904,0.00009016048,0.0001074938],"domain_scores_gemma":[0.9994527,0.00006324314,0.0001054149,0.0001954075,0.0001114622,0.0000718503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002001106,0.00002732759,0.170859,0.000114517,0.000009345643,0.000002758888,0.0002168232,3.052969e-7,0.822625,0.0001519229,0.000009583443,0.00578324],"study_design_scores_gemma":[0.0003138877,0.0001782915,0.4292775,0.00002537317,0.00003637085,0.0001332381,0.00002505794,0.00001293897,0.5697963,0.00004384819,0.0001206846,0.000036479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986863,0.000420856,0.00002683303,0.0002260661,0.00004864961,0.0005243135,0.000001741774,0.00001416269,0.00005110364],"genre_scores_gemma":[0.9958953,0.00005979476,0.003832642,0.00006014409,0.00006317806,0.00001344047,0.0000262383,0.000009501593,0.000039709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2584185,"threshold_uncertainty_score":0.2694665,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087021226200979,"score_gpt":0.2534666084356601,"score_spread":0.2425963961736503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}