{"id":"W1983585455","doi":"10.1006/bbrc.2001.5861","title":"Human Aryl Hydrocarbon Receptor Polymorphisms That Result in Loss of CYP1A1 Induction","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute","keywords":"Aryl hydrocarbon receptor; Linkage disequilibrium; Carcinogen; Biology; Subfamily; Genotype; Genetics; Receptor; Transcription factor; Haplotype; Xenobiotic; Polymorphism (computer science); In vitro; Biochemistry; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002717258,0.0007211641,0.0005262814,0.0007555673,0.0003624478,0.0002368436,0.0002415527,0.0007516604,0.004888434],"category_scores_gemma":[0.0007904966,0.0002789619,0.0004253249,0.0006505458,0.0005420555,0.0001653533,0.0002715427,0.0006523193,0.0008073232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002113211,"about_ca_system_score_gemma":0.0002415322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154846,"about_ca_topic_score_gemma":0.001097113,"domain_scores_codex":[0.9994948,0.0001541861,0.00005599944,0.0001392104,0.0000703416,0.00008550418],"domain_scores_gemma":[0.9993263,0.0002331954,0.0002057854,0.00007731198,0.00005189907,0.0001055097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007112123,0.0008524265,0.04628368,0.0001777927,0.0004983703,0.006173977,0.0003140737,0.00145569,0.921777,0.001438295,0.001252418,0.01266424],"study_design_scores_gemma":[0.00126766,0.005744847,0.4476749,0.0001135563,0.001185673,0.05366775,0.0004107186,0.004186009,0.4698159,0.002251654,0.01353341,0.0001480416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946989,0.0003445784,0.001831168,0.000207315,0.00003951035,0.00006563519,0.001322984,0.00008598742,0.001403952],"genre_scores_gemma":[0.9974664,0.0001320415,0.0006510708,0.0001017963,0.00001883526,0.00003591444,0.0007756309,0.00003701613,0.0007813181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004888434,"threshold_uncertainty_score":0.01635349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07979427251157228,"score_gpt":0.373014477992328,"score_spread":0.2932202054807557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}