{"id":"W1983660720","doi":"10.1158/0008-5472.can-08-1127","title":"Erlotinib Attenuates Homologous Recombinational Repair of Chromosomal Breaks in Human Breast Cancer Cells","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Erlotinib; RAD51; Cancer research; DNA repair; DNA damage; Epidermal growth factor receptor; Cancer; Homologous recombination; Biology; Breast cancer; Medicine; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005237649,0.0001366481,0.0001997274,0.000161359,0.0001385221,0.000007227537,0.0003355906,0.0001825182,0.0004359199],"category_scores_gemma":[0.0000365321,0.0001395857,0.0001022823,0.0003068468,0.0003507696,0.000006911834,0.0002163265,0.0002695636,0.00001015188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001325779,"about_ca_system_score_gemma":0.0004971004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001829893,"about_ca_topic_score_gemma":0.0006706154,"domain_scores_codex":[0.9981397,0.0002023163,0.0002807121,0.0004822112,0.0004265936,0.0004684216],"domain_scores_gemma":[0.9989965,0.00002931568,0.00007043752,0.0003893442,0.0004176001,0.00009680577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001025945,0.0001821326,0.01531531,0.00004657367,0.00004195154,0.00003801382,0.00009257456,0.0000648327,0.978425,0.0001203117,0.005036954,0.0005337115],"study_design_scores_gemma":[0.0007965422,0.0002628249,0.03381515,0.0000597709,0.000004099372,0.00006001601,0.0000459502,0.00003369903,0.9634501,0.000163967,0.001145945,0.0001618684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975042,0.0008700115,0.000003827849,0.0002256371,0.0001460108,0.0003151935,0.0001645112,0.00002111401,0.00074945],"genre_scores_gemma":[0.9958681,0.0006601683,0.0001130022,0.00004615819,0.0002216153,0.0002723857,0.00005381847,0.00003421971,0.002730575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01849985,"threshold_uncertainty_score":0.5692137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04013506881330303,"score_gpt":0.3536191425484176,"score_spread":0.3134840737351146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}