{"id":"W1983705436","doi":"10.1097/mbc.0000000000000273","title":"Effect of ascorbate on plasminogen activator inhibitor-1 expression and release from platelets and endothelial cells in an in-vitro model of sepsis","year":2015,"lang":"en","type":"article","venue":"Blood Coagulation & Fibrinolysis","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Victoria Park; Western University; Lawson Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"In vitro; Platelet; Sepsis; Activator (genetics); Plasminogen activator; Plasminogen activator inhibitor-1; Pharmacology; Chemistry; Medicine; Immunology; Internal medicine; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000269475,0.0001784354,0.0004378256,0.0003496596,0.00003362366,0.00002513117,0.00008522774,0.0001423202,0.000004575678],"category_scores_gemma":[0.00008781304,0.000163071,0.00004854172,0.0002101568,0.0000683655,0.0002876328,0.00007131269,0.0001392672,0.000001453021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000298893,"about_ca_system_score_gemma":0.00002451963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003816588,"about_ca_topic_score_gemma":0.00002029478,"domain_scores_codex":[0.9983503,0.0002973652,0.0003748475,0.0003679967,0.0003945123,0.0002149415],"domain_scores_gemma":[0.9991049,0.0003104013,0.0001632839,0.00024128,0.00004924678,0.0001309485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003397232,0.0001714501,0.03019898,0.0000853593,0.00001756716,0.000005881721,0.0007543027,0.003207833,0.9492861,0.000001652526,0.000006602804,0.01286705],"study_design_scores_gemma":[0.004045432,0.0006658507,0.009853653,0.0002275876,0.00005102309,9.29761e-7,0.00007049873,0.04032182,0.9445691,0.00005757491,0.000002153982,0.0001343686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993318,0.00008538201,0.00001789263,0.00002295311,0.00004213505,0.0002899555,0.0001537516,0.00001527684,0.00004083268],"genre_scores_gemma":[0.9994745,0.00001837179,0.0003831651,0.000006986924,0.00004027471,0.000009970843,0.00002919618,0.00002331148,0.0000142392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03711399,"threshold_uncertainty_score":0.6649841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02479226307309482,"score_gpt":0.2802309239176728,"score_spread":0.255438660844578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}