{"id":"W1983708816","doi":"10.1002/ddr.10285","title":"Syntheses, calcium channel modulation effects, and nitric oxide release studies of <i>O</i><sup>2</sup>‐alkyl‐1‐(pyrrolidin‐1‐yl) diazen‐1‐ium‐1,2‐diolate 4‐aryl(heteroaryl)‐1,4‐dihydro‐2,6‐dimethyl‐3‐nitropyridine‐5‐carboxylates","year":2003,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Substituent; Moiety; Alkyl; Aryl; Stereochemistry; Calcium channel; Medicinal chemistry; Calcium; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002161348,0.0005469361,0.0007276371,0.0004770996,0.0005607833,0.00009262958,0.0003728009,0.000261125,0.00001624826],"category_scores_gemma":[0.001815181,0.0004592695,0.000171526,0.0005594352,0.0004016826,0.00004780698,0.0004344685,0.0004060408,0.00001695171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007663397,"about_ca_system_score_gemma":0.0002855062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000121415,"about_ca_topic_score_gemma":0.00001404506,"domain_scores_codex":[0.9959356,0.0006325645,0.000712646,0.000935229,0.0007870179,0.0009969915],"domain_scores_gemma":[0.9976891,0.0007103621,0.0002064113,0.0005812766,0.0005345912,0.0002782876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004020792,0.0005076268,0.007454691,0.001290432,0.0008111244,0.0000377335,0.001568153,0.0009463225,0.9755589,0.0003640793,0.002183073,0.008875836],"study_design_scores_gemma":[0.000797593,0.0001569699,0.004737397,0.0003400125,0.00005352849,0.00002503248,0.001043307,0.00120097,0.976864,0.0005437142,0.01353341,0.0007040369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838824,0.01421954,0.0001730392,0.0001822884,0.0001003228,0.0006596435,0.00002315332,0.00003489675,0.0007247394],"genre_scores_gemma":[0.9935777,0.003863052,0.0009262838,0.00007621574,0.0001879719,0.0002034984,0.00006846878,0.00008209307,0.001014703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01135033,"threshold_uncertainty_score":0.9997859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04938883599579966,"score_gpt":0.3116481436821378,"score_spread":0.2622593076863382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}