{"id":"W1983708816","doi":"10.1002/ddr.10285","title":"Syntheses, calcium channel modulation effects, and nitric oxide release studies of <i>O</i><sup>2</sup>‐alkyl‐1‐(pyrrolidin‐1‐yl) diazen‐1‐ium‐1,2‐diolate 4‐aryl(heteroaryl)‐1,4‐dihydro‐2,6‐dimethyl‐3‐nitropyridine‐5‐carboxylates","year":2003,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Substituent; Moiety; Alkyl; Aryl; Stereochemistry; Calcium channel; Medicinal chemistry; Calcium; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001950179,0.0003058261,0.0002202417,0.0001139429,0.0001307232,0.0001455223,0.0002633603,0.0001621831,0.0008977464],"category_scores_gemma":[0.0001908572,0.0001326417,0.0001762673,0.0001007988,0.0001765006,0.0001609103,0.0001002078,0.0002346964,0.0003439085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002358921,"about_ca_system_score_gemma":0.0002332539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004515529,"about_ca_topic_score_gemma":0.0006956772,"domain_scores_codex":[0.9999022,0.00001769708,0.00001028884,0.00001819747,0.0000276383,0.00002392945],"domain_scores_gemma":[0.9998547,0.0000292905,0.00004965079,0.00001462192,0.00002147847,0.00003026744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005307546,0.00001330314,0.00002320774,0.0000195902,0.000001825659,0.0000278819,0.000006909183,0.00004869224,0.9992468,0.00003605036,0.00001207712,0.0005106299],"study_design_scores_gemma":[0.00001851252,0.0001899883,0.0004030669,0.000001818273,0.000005899215,0.00004902349,0.000004508043,0.0001163007,0.998486,0.000007308489,0.0007155086,0.000002074723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991486,0.001063851,0.004446187,0.0000462846,0.00003005547,0.00007271215,0.0003107159,0.00005171897,0.002492646],"genre_scores_gemma":[0.9860283,0.001263025,0.008743634,0.00005466244,0.00002565517,0.00009282729,0.0006389432,0.00003652534,0.00311649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008977464,"threshold_uncertainty_score":0.00300324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04938883599579966,"score_gpt":0.3116481436821378,"score_spread":0.2622593076863382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}