{"id":"W1983730319","doi":"10.1016/j.clon.2011.10.016","title":"Clinical Outcomes of a Phase II Open-labelled, Randomised Study Investigating the Tolerability and Efficacy of Anti-androgen Manipulation versus Taxotere and Anti-androgen Manipulation in Patients with Hormone Naive High Risk/Metastatic Prostate Cancer","year":2012,"lang":"en","type":"article","venue":"Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Tolerability; Androgen; Internal medicine; Oncology; Hormone; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003527583,0.0002176792,0.001592301,0.0000816024,0.0001437675,0.0000125632,0.0001309788,0.0001514162,0.00001916631],"category_scores_gemma":[0.002121661,0.0001240755,0.00009294834,0.0002412831,0.0007514812,0.0001827591,0.0002777849,0.0004465663,7.499946e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009162374,"about_ca_system_score_gemma":0.0002777451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007946579,"about_ca_topic_score_gemma":0.00016008,"domain_scores_codex":[0.9958897,0.001366684,0.001675762,0.0004410149,0.0003100341,0.0003168073],"domain_scores_gemma":[0.9948558,0.003170935,0.001160701,0.0003357364,0.0002386174,0.0002382388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03906413,0.009994022,0.9225549,0.00005253423,0.000865786,0.000007246777,0.001204911,0.00001590007,0.00001712406,0.000006861651,0.00001086882,0.0262058],"study_design_scores_gemma":[0.2484523,0.01238487,0.7376503,0.00004946768,0.0008112162,9.332419e-7,0.0002719749,0.0002242552,0.00002546752,0.00002393356,0.00001325736,0.00009202569],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928411,0.0006024806,0.000004391078,0.0003413895,0.0001816345,0.005958176,0.00004539574,0.000009097549,0.00001631752],"genre_scores_gemma":[0.9986217,0.0005696713,0.0004598149,0.00005162186,0.00005077618,0.0001442222,0.00006594945,0.00002021992,0.00001604038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2093882,"threshold_uncertainty_score":0.5059652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1598036510852493,"score_gpt":0.4679541563365681,"score_spread":0.3081505052513188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}