{"id":"W1983736629","doi":"10.1016/j.celrep.2015.01.052","title":"A Cell-Signaling Network Temporally Resolves Specific versus Promiscuous Phosphorylation","year":2015,"lang":"en","type":"article","venue":"Cell Reports","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Syddansk Universitet","keywords":"Phosphorylation; Cell biology; Signal transduction; Cell; Cell signaling; Computational biology; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005646947,0.0001804045,0.0001516822,0.00002278575,0.00009152165,0.00005016323,0.0001031645,0.0001760304,0.0000401439],"category_scores_gemma":[0.00005153232,0.0001767485,0.00009217752,0.00009596072,0.00004267933,0.000005189477,0.00008897599,0.0001105587,0.00002967127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002609825,"about_ca_system_score_gemma":0.0001972061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001248294,"about_ca_topic_score_gemma":0.00000328538,"domain_scores_codex":[0.998597,0.00005824338,0.0003470959,0.0004620997,0.0002202158,0.0003153502],"domain_scores_gemma":[0.9989129,0.00001000179,0.0002621882,0.0004942549,0.0001270244,0.0001936098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007605267,0.000147592,0.005592527,0.00005100454,0.00003204667,0.0005080931,0.0003035351,0.002059085,0.8769132,0.00002048021,0.1123355,0.001276412],"study_design_scores_gemma":[0.0005848577,0.0003298997,0.00009123205,0.0000134566,0.00001243897,0.00004261199,0.00008187412,0.0000194757,0.7344283,0.0002308668,0.2639293,0.0002357176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9252512,0.007842888,0.0007012055,0.00002707803,0.00109619,0.0004140672,0.000002416367,0.00004766941,0.0646173],"genre_scores_gemma":[0.9920719,0.00008535106,0.003275033,0.00004585885,0.0009528117,0.00003323301,0.0001909104,0.00003830214,0.003306584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1515938,"threshold_uncertainty_score":0.7207595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03004362791675875,"score_gpt":0.2396524146287639,"score_spread":0.2096087867120051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}