{"id":"W1983751237","doi":"10.1002/chin.200040143","title":"ChemInform Abstract: From Serine to Functionalized Enantiopure Tetrahydroisoquinolines.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Enantiopure drug; Chemistry; Combinatorial chemistry; Organic chemistry; Enantioselective synthesis; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002941175,0.0007216766,0.0003225721,0.0003872723,0.0002025604,0.0003799533,0.0006444083,0.0002911896,0.01512684],"category_scores_gemma":[0.0002102621,0.0002035345,0.0003341018,0.0003413868,0.0002027206,0.000564967,0.0004503407,0.0008151667,0.008661157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004614393,"about_ca_system_score_gemma":0.0005137114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006537726,"about_ca_topic_score_gemma":0.0008801986,"domain_scores_codex":[0.9998624,0.00001704716,0.000009776561,0.00002787299,0.00004584422,0.00003695527],"domain_scores_gemma":[0.9999493,0.000006994614,0.000008833507,0.000006078788,0.00001027927,0.0000184899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007053607,0.0001179977,0.0001320124,0.00115245,0.0000661728,0.0006431484,0.0001391265,0.001129644,0.8742695,0.01122116,0.02418598,0.08623745],"study_design_scores_gemma":[0.0001390885,0.0007471247,0.000369047,0.00007242322,0.00005213645,0.0005372958,0.00002865721,0.0006037226,0.787783,0.001571001,0.2080618,0.00003480662],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.3285851,0.08209331,0.1699321,0.003607048,0.006163321,0.0008265355,0.01459916,0.01035332,0.3838401],"genre_scores_gemma":[0.7681667,0.04982349,0.0357113,0.001302563,0.0004373203,0.0001983329,0.009327644,0.0009819543,0.1340506],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.01512684,"threshold_uncertainty_score":0.05060434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225680113005956,"score_gpt":0.2313607737900527,"score_spread":0.2191039726599932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}